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Dynamic Regulation of Host Restriction Factor Expression over the Course of HIV-1 Infection In Vivo

Overview of attention for article published in Journal of Virology, July 2014
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Title
Dynamic Regulation of Host Restriction Factor Expression over the Course of HIV-1 Infection In Vivo
Published in
Journal of Virology, July 2014
DOI 10.1128/jvi.01771-14
Pubmed ID
Authors

Rui André Saraiva Raposo, Mohamed Abdel-Mohsen, Xutao Deng, Frederick M. Hecht, Christopher D. Pilcher, Satish K. Pillai, Douglas F. Nixon

Abstract

In this study, we investigated the expression levels of host restriction factors in six untreated HIV-1-positive patients over the course of infection. We found that the host restriction factor gene expression profile consistently increased over time and significantly associated with CD4(+) T cell activation and viral load. Our data are among the first to demonstrate the dynamic nature of host restriction factors in vivo over time.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 7%
Spain 1 4%
Unknown 24 89%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 19%
Student > Bachelor 5 19%
Student > Ph. D. Student 3 11%
Student > Postgraduate 3 11%
Student > Master 3 11%
Other 4 15%
Unknown 4 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 10 37%
Immunology and Microbiology 8 30%
Medicine and Dentistry 3 11%
Biochemistry, Genetics and Molecular Biology 2 7%
Unknown 4 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 November 2014.
All research outputs
#19,942,887
of 25,371,288 outputs
Outputs from Journal of Virology
#23,221
of 25,689 outputs
Outputs of similar age
#167,483
of 241,797 outputs
Outputs of similar age from Journal of Virology
#177
of 222 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 25,689 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.5. This one is in the 8th percentile – i.e., 8% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 241,797 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 222 others from the same source and published within six weeks on either side of this one. This one is in the 19th percentile – i.e., 19% of its contemporaries scored the same or lower than it.