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Role of MicroRNA Modulation in the Interferon-α/Ribavirin Suppression of HIV-1 In Vivo

Overview of attention for article published in PLOS ONE, October 2014
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (54th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (56th percentile)

Mentioned by

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6 X users

Citations

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7 Dimensions

Readers on

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31 Mendeley
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Title
Role of MicroRNA Modulation in the Interferon-α/Ribavirin Suppression of HIV-1 In Vivo
Published in
PLOS ONE, October 2014
DOI 10.1371/journal.pone.0109220
Pubmed ID
Authors

Mohamed Abdel-Mohsen, Xutao Deng, Ali Danesh, Teri Liegler, Evan S. Jacobs, Andri Rauch, Bruno Ledergerber, Philip J. Norris, Huldrych F. Günthard, Joseph K. Wong, Satish K. Pillai

Abstract

Interferon-α (IFN-α) treatment suppresses HIV-1 viremia and reduces the size of the HIV-1 latent reservoir. Therefore, investigation of the molecular and immunologic effects of IFN-α may provide insights that contribute to the development of novel prophylactic, therapeutic and curative strategies for HIV-1 infection. In this study, we hypothesized that microRNAs (miRNAs) contribute to the IFN-α-mediated suppression of HIV-1. To inform the development of novel miRNA-based antiretroviral strategies, we investigated the effects of exogenous IFN-α treatment on global miRNA expression profile, HIV-1 viremia, and potential regulatory networks between miRNAs and cell-intrinsic anti-HIV-1 host factors in vivo.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 3%
Unknown 30 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 32%
Student > Ph. D. Student 8 26%
Student > Bachelor 4 13%
Student > Master 2 6%
Student > Doctoral Student 1 3%
Other 1 3%
Unknown 5 16%
Readers by discipline Count As %
Medicine and Dentistry 7 23%
Agricultural and Biological Sciences 6 19%
Biochemistry, Genetics and Molecular Biology 4 13%
Immunology and Microbiology 3 10%
Computer Science 1 3%
Other 2 6%
Unknown 8 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 November 2023.
All research outputs
#8,473,367
of 25,286,324 outputs
Outputs from PLOS ONE
#112,124
of 219,398 outputs
Outputs of similar age
#86,587
of 260,865 outputs
Outputs of similar age from PLOS ONE
#2,062
of 5,306 outputs
Altmetric has tracked 25,286,324 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 219,398 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.7. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 260,865 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.
We're also able to compare this research output to 5,306 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.