You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
Mendeley readers
Attention Score in Context
| Title |
Atrial Fibrillation Produced by Prolonged Rapid Atrial Pacing Is Associated With Heterogeneous Changes in Atrial Sympathetic Innervation
|
|---|---|
| Published in |
Circulation, March 2000
|
| DOI | 10.1161/01.cir.101.10.1185 |
| Pubmed ID | |
| Authors |
J. Vijay Jayachandran, Haris J. Sih, Wendy Winkle, Douglas P. Zipes, Gary D. Hutchins, Jeffrey E. Olgin |
| Abstract |
Structural and electrophysiological changes of the atria occur with prolonged rapid rates; however, the effects of sustained atrial fibrillation (AF) on autonomic innervation of the atria are unknown. We hypothesized that electrophysiological remodeling from rapid atrial rates is accompanied by altered atrial autonomic innervation. Six dogs (paced group) underwent atrial pacing at 600 bpm; 9 dogs (control animals) were not paced. All paced dogs developed sustained AF by week 4 of pacing. All 15 animals underwent positron emission tomography imaging of the atria with [C-11] hydroxyephedrine (HED) to label sympathetic nerve terminals. HED retention in the atria was significantly greater in paced dogs compared with control animals (P=0.03). Tissue samples from the atrial appendages had a greater concentration of norepinephrine in paced animals than in control animals (P=0.01). The coefficient of variation of HED retention was also greater in paced animals (P=0.05) and was greater in the right atrium than in the left atrium (P=0.004). Epicardial activation maps of AF were obtained in the paced animals at baseline and with autonomic manipulation. Mean AF cycle length was longer in the right atrium (109.2+/-5 ms) than in the left atrium (85.8+/-5.5 ms) at baseline (P=0.005). AF cycle length did not vary significantly from baseline (97.6+/-13.4 ms) with stellate stimulation (100.5+/-6 ms) but lengthened with propranolol (107.5+/-6.1 ms, P=0.03). Rapid rates of AF produce a heterogeneous increase in atrial sympathetic innervation. These changes parallel disparate effects of rapid pacing-induced AF on atrial electrophysiology. |
Mendeley readers
The data shown below were compiled from readership statistics for 68 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 1% |
| United Kingdom | 1 | 1% |
| Spain | 1 | 1% |
| United States | 1 | 1% |
| Unknown | 64 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 13 | 19% |
| Student > Ph. D. Student | 11 | 16% |
| Other | 6 | 9% |
| Student > Bachelor | 5 | 7% |
| Student > Master | 5 | 7% |
| Other | 11 | 16% |
| Unknown | 17 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 29 | 43% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 7% |
| Engineering | 3 | 4% |
| Physics and Astronomy | 3 | 4% |
| Agricultural and Biological Sciences | 3 | 4% |
| Other | 8 | 12% |
| Unknown | 17 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 January 2008.
All research outputs
#8,568,232
of 25,450,869 outputs
Outputs from Circulation
#12,093
of 21,123 outputs
Outputs of similar age
#13,753
of 41,554 outputs
Outputs of similar age from Circulation
#70
of 149 outputs
Altmetric has tracked 25,450,869 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 21,123 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 31.4. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 41,554 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 149 others from the same source and published within six weeks on either side of this one. This one is in the 6th percentile – i.e., 6% of its contemporaries scored the same or lower than it.