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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Bilateral adaptive deep brain stimulation is effective in Parkinson's disease
|
|---|---|
| Published in |
Journal of neurology, neurosurgery and psychiatry, September 2015
|
| DOI | 10.1136/jnnp-2015-310972 |
| Pubmed ID | |
| Authors |
Simon Little, Martijn Beudel, Ludvic Zrinzo, Thomas Foltynie, Patricia Limousin, Marwan Hariz, Spencer Neal, Binith Cheeran, Hayriye Cagnan, James Gratwicke, Tipu Z Aziz, Alex Pogosyan, Peter Brown |
| Abstract |
Adaptive deep brain stimulation (aDBS) uses feedback from brain signals to guide stimulation. A recent acute trial of unilateral aDBS showed that aDBS can lead to substantial improvements in contralateral hemibody Unified Parkinson's Disease Rating Scale (UPDRS) motor scores and may be superior to conventional continuous DBS in Parkinson's disease (PD). We test whether potential benefits are retained with bilateral aDBS and in the face of concurrent medication. We applied bilateral aDBS in 4 patients with PD undergoing DBS of the subthalamic nucleus. aDBS was delivered bilaterally with independent triggering of stimulation according to the amplitude of β activity at the corresponding electrode. Mean stimulation voltage was 3.0±0.1 volts. Motor assessments consisted of double-blinded video-taped motor UPDRS scores that included both limb and axial features. UPDRS scores were 43% (p=0.04; Cohen's d=1.62) better with aDBS than without stimulation. Motor improvement with aDBS occurred despite an average time on stimulation (ToS) of only 45%. Levodopa was well tolerated during aDBS and led to further reductions in ToS. Bilateral aDBS can improve both axial and limb symptoms and can track the need for stimulation across drug states. |
X Demographics
The data shown below were collected from the profiles of 17 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 29% |
| United Kingdom | 2 | 12% |
| Switzerland | 1 | 6% |
| Australia | 1 | 6% |
| Netherlands | 1 | 6% |
| Unknown | 7 | 41% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 12 | 71% |
| Scientists | 3 | 18% |
| Practitioners (doctors, other healthcare professionals) | 1 | 6% |
| Science communicators (journalists, bloggers, editors) | 1 | 6% |
Mendeley readers
The data shown below were compiled from readership statistics for 344 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| France | 1 | <1% |
| Romania | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 340 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 60 | 17% |
| Student > Ph. D. Student | 57 | 17% |
| Student > Master | 40 | 12% |
| Student > Bachelor | 27 | 8% |
| Other | 23 | 7% |
| Other | 55 | 16% |
| Unknown | 82 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 84 | 24% |
| Medicine and Dentistry | 48 | 14% |
| Engineering | 41 | 12% |
| Agricultural and Biological Sciences | 20 | 6% |
| Psychology | 11 | 3% |
| Other | 30 | 9% |
| Unknown | 110 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 30. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 December 2022.
All research outputs
#1,311,023
of 25,394,764 outputs
Outputs from Journal of neurology, neurosurgery and psychiatry
#534
of 7,408 outputs
Outputs of similar age
#18,597
of 286,428 outputs
Outputs of similar age from Journal of neurology, neurosurgery and psychiatry
#10
of 88 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,408 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.9. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 286,428 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 88 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.