Title |
Seroprevalence of leptospiral antibodies among market workers and food handlers in the central state of Malaysia
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Published in |
Tropical Medicine & International Health, March 2018
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DOI | 10.1111/tmi.13033 |
Pubmed ID | |
Authors |
S. Samsudin, S. N. S. Sakinah, O. Malina, B. A. Norliza, M. A. Noh, A. Fairuz, T. Z. M. T. Jamaluddin, R. A. Hamat, W. M. Zahiruddin, S. Mohd Nazri, S. Sukeri, B. D. Aziah, I. Zawaha, A. W. Zainudin, N. A. Munirah, M. N. Desa, V. Neela, S. N. Masri |
Abstract |
The high prevalence of leptospirosis in humans is of great public health concern, particularly in tropical and subtropical regions. This study aimed to determine the seroprevalence of Leptospira antibodies and distribution of serovars, and to assess the usefulness of enzyme-linked immunosorbent assay (ELISA) as a screening method for leptospiral antibodies in a high-risk healthy community. Cross-sectional study of 231 market workers and food handlers in wet markets and food premises from two localities in central Malaysia. Respondents' background information was obtained using a questionnaire. Serum samples were tested for Leptospira antibodies using ELISA and microscopic agglutination test (MAT). Seroprevalence of leptospirosis among healthy workers was 46.3%. Detection of seropositivity was higher by MAT (46%) than ELISA (15%). We observed high seropositivity among local workers (49%), food handlers (49.5%), females (60.8%), and those aged 34 years and older (46.3%). Local strain LEP175 was the predominant serovar, followed by WHO strain Patoc. Overall seroprevalence among healthy food handlers and market workers was high in this study. The workplace places susceptible individuals at risk of leptospirosis. This article is protected by copyright. All rights reserved. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Malaysia | 1 | 25% |
United States | 1 | 25% |
Unknown | 2 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 73 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 10 | 14% |
Student > Bachelor | 9 | 12% |
Researcher | 6 | 8% |
Other | 4 | 5% |
Lecturer | 4 | 5% |
Other | 15 | 21% |
Unknown | 25 | 34% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 11 | 15% |
Biochemistry, Genetics and Molecular Biology | 8 | 11% |
Immunology and Microbiology | 6 | 8% |
Veterinary Science and Veterinary Medicine | 5 | 7% |
Nursing and Health Professions | 3 | 4% |
Other | 11 | 15% |
Unknown | 29 | 40% |