| Title |
Severe Acute Respiratory Infection (SARI) sentinel surveillance in the country of Georgia, 2015-2017
|
|---|---|
| Published in |
PLOS ONE, July 2018
|
| DOI | 10.1371/journal.pone.0201497 |
| Pubmed ID | |
| Authors |
Giorgi Chakhunashvili, Abram L. Wagner, Laura E. Power, Cara B. Janusz, Ann Machablishvili, Irakli Karseladze, Olgha Tarkhan-Mouravi, Khatuna Zakhashvili, Paata Imnadze, Gregory C. Gray, Benjamin Anderson, Matthew L. Boulton |
| Abstract |
Severe Acute Respiratory Infection (SARI) causes substantial mortality and morbidity worldwide. The country of Georgia conducts sentinel surveillance to monitor SARI activity and changes in its infectious etiology. This study characterizes the epidemiology of SARI in Georgia over the 2015/16 and 2016/17 influenza seasons, compares clinical presentations by etiology, and estimates influenza vaccine effectiveness using a test-negative design. SARI cases were selected through alternate day systematic sampling between September 2015 and March 2017 at five sentinel surveillance inpatient sites. Nasopharyngeal swabs were tested for respiratory viruses and Mycoplasma pneumoniae using a multiplex diagnostic system. We present SARI case frequencies by demographic characteristics, co-morbidities, and clinical presentation, and used logistic regression to estimate influenza A vaccine effectiveness. 1,624 patients with SARI were identified. More cases occurred in February (28.7%; 466/1624) than other months. Influenza was the dominant pathogen in December-February, respiratory syncytial virus in March-May, and rhinovirus in June-November. Serious clinical symptoms including breathing difficulties, ICU hospitalization, and artificial ventilation were common among influenza A and human metapneumovirus cases. For influenza A/H3, a protective association between vaccination and disease status was observed when cases with unknown vaccination status were combined with those who were unvaccinated (OR: 0.53, 95% CI: 0.30, 0.97). Multi-pathogen diagnostic testing through Georgia's sentinel surveillance provides useful information on etiology, seasonality, and demographic associations. Influenza A and B were associated with more severe outcomes, although the majority of the population studied was unvaccinated. Findings from sentinel surveillance can assist in prevention planning. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 101 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 101 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 18 | 18% |
| Student > Master | 10 | 10% |
| Student > Ph. D. Student | 9 | 9% |
| Student > Bachelor | 7 | 7% |
| Other | 6 | 6% |
| Other | 16 | 16% |
| Unknown | 35 | 35% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 28 | 28% |
| Agricultural and Biological Sciences | 6 | 6% |
| Biochemistry, Genetics and Molecular Biology | 5 | 5% |
| Nursing and Health Professions | 5 | 5% |
| Immunology and Microbiology | 3 | 3% |
| Other | 13 | 13% |
| Unknown | 41 | 41% |
Attention Score in Context
This research output has an Altmetric Attention Score of 166. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 June 2023.
All research outputs
#207,913
of 23,098,660 outputs
Outputs from PLOS ONE
#3,121
of 197,109 outputs
Outputs of similar age
#4,957
of 329,967 outputs
Outputs of similar age from PLOS ONE
#57
of 3,274 outputs
Altmetric has tracked 23,098,660 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 197,109 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.2. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,967 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 3,274 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.