Title |
Does low serum 25 OH vitamin D interact with very strenuous physical activity, facilitating development of rhabdomyolysis?
|
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Published in |
Medical Hypotheses, July 2013
|
DOI | 10.1016/j.mehy.2013.06.029 |
Pubmed ID | |
Authors |
Brandon N. Conrad, Charles J. Glueck |
Abstract |
Vitamin D plays an important and increasingly understood role in muscle health and performance. Vitamin D exhibits a nuclear receptor for transcription interaction and a transmembrane receptor, giving it genomic and non-genomic interactions. Vitamin D receptors have been described that affect muscle function. Vitamin D has also been correlated with muscle performance. Beyond its role in normal muscle function, vitamin D deficiency can interact with statins to produce myalgia-myositis, which can be reversed by normalizing serum vitamin D [7,13]. Exertional rhabdomyolysis may occur in diverse settings including marathons, ice skating, bicycling and swimming. Our hypothesis is that subjects with pre-existing low serum 25OHD are selected out for exertional rhabdomyolysis during strenuous activities. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 33% |
Demographic breakdown
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Members of the public | 2 | 67% |
Scientists | 1 | 33% |
Mendeley readers
Geographical breakdown
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United States | 1 | 2% |
Unknown | 46 | 96% |
Demographic breakdown
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Student > Master | 12 | 25% |
Researcher | 7 | 15% |
Other | 3 | 6% |
Student > Ph. D. Student | 3 | 6% |
Student > Bachelor | 3 | 6% |
Other | 10 | 21% |
Unknown | 10 | 21% |
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Sports and Recreations | 8 | 17% |
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Neuroscience | 2 | 4% |
Other | 6 | 13% |
Unknown | 15 | 31% |