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X Demographics
Mendeley readers
Attention Score in Context
| Title |
A Kinesin-14 Motor Activates Neocentromeres to Promote Meiotic Drive in Maize
|
|---|---|
| Published in |
Cell, April 2018
|
| DOI | 10.1016/j.cell.2018.03.009 |
| Pubmed ID | |
| Authors |
R. Kelly Dawe, Elizabeth G. Lowry, Jonathan I. Gent, Michelle C. Stitzer, Kyle W. Swentowsky, David M. Higgins, Jeffrey Ross-Ibarra, Jason G. Wallace, Lisa B. Kanizay, Magdy Alabady, Weihong Qiu, Kuo-Fu Tseng, Na Wang, Zhi Gao, James A. Birchler, Alex E. Harkess, Amy L. Hodges, Evelyn N. Hiatt |
| Abstract |
Maize abnormal chromosome 10 (Ab10) encodes a classic example of true meiotic drive that converts heterochromatic regions called knobs into motile neocentromeres that are preferentially transmitted to egg cells. Here, we identify a cluster of eight genes on Ab10, called the Kinesin driver (Kindr) complex, that are required for both neocentromere motility and preferential transmission. Two meiotic drive mutants that lack neocentromere activity proved to be kindr epimutants with increased DNA methylation across the entire gene cluster. RNAi of Kindr induced a third epimutant and corresponding loss of meiotic drive. Kinesin gliding assays and immunolocalization revealed that KINDR is a functional minus-end-directed kinesin that localizes specifically to knobs containing 180 bp repeats. Sequence comparisons suggest that Kindr diverged from a Kinesin-14A ancestor ∼12 mya and has driven the accumulation of > 500 Mb of knob repeats and affected the segregation of thousands of genes linked to knobs on all 10 chromosomes. |
X Demographics
The data shown below were collected from the profiles of 180 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 81 | 45% |
| United Kingdom | 7 | 4% |
| Germany | 6 | 3% |
| Australia | 4 | 2% |
| Georgia | 4 | 2% |
| Canada | 4 | 2% |
| France | 3 | 2% |
| India | 2 | 1% |
| Curaçao | 1 | <1% |
| Other | 15 | 8% |
| Unknown | 53 | 29% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 101 | 56% |
| Members of the public | 71 | 39% |
| Science communicators (journalists, bloggers, editors) | 6 | 3% |
| Practitioners (doctors, other healthcare professionals) | 2 | 1% |
Mendeley readers
The data shown below were compiled from readership statistics for 149 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 149 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 39 | 26% |
| Researcher | 24 | 16% |
| Student > Bachelor | 20 | 13% |
| Student > Master | 8 | 5% |
| Student > Doctoral Student | 7 | 5% |
| Other | 19 | 13% |
| Unknown | 32 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 69 | 46% |
| Biochemistry, Genetics and Molecular Biology | 36 | 24% |
| Medicine and Dentistry | 3 | 2% |
| Engineering | 2 | 1% |
| Chemistry | 2 | 1% |
| Other | 2 | 1% |
| Unknown | 35 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 120. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 April 2023.
All research outputs
#356,059
of 25,843,331 outputs
Outputs from Cell
#1,921
of 17,302 outputs
Outputs of similar age
#7,969
of 344,614 outputs
Outputs of similar age from Cell
#58
of 168 outputs
Altmetric has tracked 25,843,331 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 17,302 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 59.8. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 344,614 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 168 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.