Title |
Immune responses to Schistosoma haematobium infection
|
---|---|
Published in |
Parasite Immunology, September 2014
|
DOI | 10.1111/pim.12084 |
Pubmed ID | |
Authors |
J. I. Odegaard, M. H. Hsieh |
Abstract |
Urogenital schistosomiasis is one of the greatest single infectious sources of human morbidity and mortality known. Through a complex cycle of infection, migration and eventual maturation and mating, S. haematobium (the aetiological agent of urogenital schistosomiasis) deposits highly immunogenic eggs within the bladder and other pelvic organs, activating a wide range of immune programs that determine both infection outcome as well as downstream immunopathology. In this review, we discuss the experimental and observational bases for our current understanding of these immune programs, focusing specifically on how the balance of type 1 and type 2 responses governs subsequent immunopathology and clinical outcome. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Switzerland | 1 | <1% |
Unknown | 104 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 20 | 19% |
Student > Master | 18 | 17% |
Student > Ph. D. Student | 11 | 10% |
Researcher | 9 | 9% |
Student > Doctoral Student | 5 | 5% |
Other | 16 | 15% |
Unknown | 26 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Immunology and Microbiology | 21 | 20% |
Biochemistry, Genetics and Molecular Biology | 16 | 15% |
Medicine and Dentistry | 15 | 14% |
Agricultural and Biological Sciences | 12 | 11% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 3% |
Other | 9 | 9% |
Unknown | 29 | 28% |