Title |
Omega 3 fatty acids in cardiovascular disease risk factors: An updated systematic review of randomised clinical trials
|
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Published in |
Clinical Nutrition, May 2017
|
DOI | 10.1016/j.clnu.2017.05.015 |
Pubmed ID | |
Authors |
Oscar D. Rangel-Huerta, Angel Gil |
Abstract |
Several studies and reviews regarding the supplementation of omega-3 LC-PUFAs have been developed during the last years. Indeed, the evidence states that high doses omega-3 LC-PUFAs produce a small but significant decrease in blood pressure in older and hypertensive subjects. Due to the increasing interest in the benefits of LC-PUFAs, we aimed to evaluate the scientific evidence provided in the past five years (2012-2016) on the effects of the intake of omega-3 LC-PUFAs on cardiovascular risk factors such as inflammation and oxidative stress, through a systematic review in PubMed database. Twenty-eight articles were related to cardiovascular disease (CVD) and are included in this systematic review. The studies included healthy subjects and CVD patients; we included the number of subjects, type of study, type and doses of omega-3 LC-PUFAs, primary outcomes, and results. The use of omega-3 LC-PUFAs for ameliorating CVD risk factors can be recommended. However, the administration of omega-3 does not seem to show any benefit for the management of CVD or associated complications. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Spain | 2 | 33% |
United Kingdom | 1 | 17% |
Unknown | 3 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 4 | 67% |
Practitioners (doctors, other healthcare professionals) | 2 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | <1% |
Unknown | 129 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 21 | 16% |
Student > Master | 20 | 15% |
Student > Bachelor | 17 | 13% |
Student > Ph. D. Student | 7 | 5% |
Other | 7 | 5% |
Other | 29 | 22% |
Unknown | 29 | 22% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 22 | 17% |
Nursing and Health Professions | 19 | 15% |
Biochemistry, Genetics and Molecular Biology | 15 | 12% |
Agricultural and Biological Sciences | 13 | 10% |
Social Sciences | 4 | 3% |
Other | 16 | 12% |
Unknown | 41 | 32% |