Title |
Estimated Incidence of Antimicrobial Drug–Resistant Nontyphoidal Salmonella Infections, United States, 2004–2012 - Volume 23, Number 1—January 2017 - Emerging Infectious Diseases journal - CDC
|
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Published in |
Emerging Infectious Diseases, January 2016
|
DOI | 10.3201/eid2301.160771 |
Pubmed ID | |
Authors |
Felicita Medalla, Weidong Gu, Barbara E. Mahon, Michael Judd, Jason Folster, Patricia M. Griffin, Robert M. Hoekstra |
Abstract |
Salmonella infections are a major cause of illness in the United States. The antimicrobial agents used to treat severe infections include ceftriaxone, ciprofloxacin, and ampicillin. Antimicrobial drug resistance has been associated with adverse clinical outcomes. To estimate the incidence of resistant culture-confirmed nontyphoidal Salmonella infections, we used Bayesian hierarchical models of 2004-2012 data from the Centers for Disease Control and Prevention National Antimicrobial Resistance Monitoring System and Laboratory-based Enteric Disease Surveillance. We based 3 mutually exclusive resistance categories on susceptibility testing: ceftriaxone and ampicillin resistant, ciprofloxacin nonsusceptible but ceftriaxone susceptible, and ampicillin resistant but ceftriaxone and ciprofloxacin susceptible. We estimated the overall incidence of resistant infections as 1.07/100,000 person-years for ampicillin-only resistance, 0.51/100,000 person-years for ceftriaxone and ampicillin resistance, and 0.35/100,000 person-years for ciprofloxacin nonsusceptibility, or ≈6,200 resistant culture-confirmed infections annually. These national estimates help define the magnitude of the resistance problem so that control measures can be appropriately targeted. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 9 | 47% |
Japan | 1 | 5% |
Unknown | 9 | 47% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 12 | 63% |
Practitioners (doctors, other healthcare professionals) | 7 | 37% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Mozambique | 1 | 1% |
Unknown | 91 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 15 | 16% |
Student > Ph. D. Student | 12 | 13% |
Student > Doctoral Student | 8 | 9% |
Student > Bachelor | 8 | 9% |
Researcher | 7 | 8% |
Other | 8 | 9% |
Unknown | 34 | 37% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 12 | 13% |
Veterinary Science and Veterinary Medicine | 11 | 12% |
Biochemistry, Genetics and Molecular Biology | 9 | 10% |
Immunology and Microbiology | 8 | 9% |
Medicine and Dentistry | 4 | 4% |
Other | 12 | 13% |
Unknown | 36 | 39% |