Title |
Effects of Zika Virus Strain and Aedes Mosquito Species on Vector Competence - Volume 23, Number 7—July 2017 - Emerging Infectious Diseases journal - CDC
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Published in |
Emerging Infectious Diseases, July 2017
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DOI | 10.3201/eid2307.161633 |
Pubmed ID | |
Authors |
Alexander T. Ciota, Sean M. Bialosuknia, Steven D. Zink, Matthew Brecher, Dylan J. Ehrbar, Madeline N. Morrissette, Laura D. Kramer |
Abstract |
In the Western Hemisphere, Zika virus is thought to be transmitted primarily by Aedes aegypti mosquitoes. To determine the extent to which Ae. albopictus mosquitoes from the United States are capable of transmitting Zika virus and the influence of virus dose, virus strain, and mosquito species on vector competence, we evaluated multiple doses of representative Zika virus strains in Ae. aegypti and Ae. albopictus mosquitoes. Virus preparation (fresh vs. frozen) significantly affected virus infectivity in mosquitoes. We calculated 50% infectious doses to be 6.1-7.5 log10 PFU/mL; minimum infective dose was 4.2 log10 PFU/mL. Ae. albopictus mosquitoes were more susceptible to infection than Ae. aegypti mosquitoes, but transmission efficiency was higher for Ae. aegypti mosquitoes, indicating a transmission barrier in Ae. albopictus mosquitoes. Results suggest that, although Zika virus transmission is relatively inefficient overall and dependent on virus strain and mosquito species, Ae. albopictus mosquitoes could become major vectors in the Americas. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 4 | 36% |
Venezuela, Bolivarian Republic of | 1 | 9% |
United Kingdom | 1 | 9% |
Brazil | 1 | 9% |
Unknown | 4 | 36% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 8 | 73% |
Scientists | 3 | 27% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 146 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 25 | 17% |
Researcher | 23 | 16% |
Student > Master | 23 | 16% |
Student > Bachelor | 16 | 11% |
Student > Doctoral Student | 11 | 8% |
Other | 23 | 16% |
Unknown | 25 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 42 | 29% |
Biochemistry, Genetics and Molecular Biology | 28 | 19% |
Immunology and Microbiology | 16 | 11% |
Medicine and Dentistry | 7 | 5% |
Environmental Science | 4 | 3% |
Other | 20 | 14% |
Unknown | 29 | 20% |