Title |
Evaluation of 5 Commercially Available Zika Virus Immunoassays
|
---|---|
Published in |
Emerging Infectious Diseases, September 2017
|
DOI | 10.3201/eid2309.162043 |
Pubmed ID | |
Authors |
David Safronetz, Angela Sloan, Derek R. Stein, Emelissa Mendoza, Nicole Barairo, Charlene Ranadheera, Leanne Scharikow, Kimberly Holloway, Alyssia Robinson, Maya Traykova-Andonova, Kai Makowski, Kristina Dimitrova, Elizabeth Giles, Joanne Hiebert, Rhonda Mogk, Sharla Beddome, Michael Drebot |
Abstract |
Because of global spread of Zika virus, accurate and high-throughput diagnostic immunoassays are needed. We compared the sensitivity and specificity of 5 commercially available Zika virus serologic assays to the recommended protocol of Zika virus IgM-capture ELISA and plaque-reduction neutralization tests. Most commercial immunoassays showed low sensitivity, which can be increased. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 8 | 33% |
India | 2 | 8% |
Nepal | 2 | 8% |
Netherlands | 1 | 4% |
Mexico | 1 | 4% |
Switzerland | 1 | 4% |
Unknown | 9 | 38% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 15 | 63% |
Practitioners (doctors, other healthcare professionals) | 5 | 21% |
Scientists | 3 | 13% |
Science communicators (journalists, bloggers, editors) | 1 | 4% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 96 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 23 | 24% |
Student > Master | 17 | 18% |
Student > Ph. D. Student | 11 | 11% |
Student > Bachelor | 9 | 9% |
Student > Doctoral Student | 8 | 8% |
Other | 14 | 15% |
Unknown | 14 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 21 | 22% |
Agricultural and Biological Sciences | 18 | 19% |
Biochemistry, Genetics and Molecular Biology | 12 | 13% |
Immunology and Microbiology | 12 | 13% |
Nursing and Health Professions | 5 | 5% |
Other | 6 | 6% |
Unknown | 22 | 23% |