Title |
Borrelia miyamotoi sensu lato Seroreactivity and Seroprevalence in the Northeastern United States - Volume 20, Number 7—July 2014 - Emerging Infectious Diseases journal - CDC
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Published in |
Emerging Infectious Diseases, July 2014
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DOI | 10.3201/eid2007.131587 |
Pubmed ID | |
Authors |
Peter J. Krause, Sukanya Narasimhan, Gary P. Wormser, Alan G. Barbour, Alexander E. Platonov, Janna Brancato, Timothy Lepore, Kenneth Dardick, Mark Mamula, Lindsay Rollend, Tanner K. Steeves, Maria Diuk-Wasser, Sahar Usmani-Brown, Phillip Williamson, Denis S. Sarksyan, Erol Fikrig, Durland Fish |
Abstract |
Borrelia miyamotoi sensu lato, a relapsing fever Borrelia sp., is transmitted by the same ticks that transmit B. burgdorferi (the Lyme disease pathogen) and occurs in all Lyme disease-endemic areas of the United States. To determine the seroprevalence of IgG against B. miyamotoi sensu lato in the northeastern United States and assess whether serum from B. miyamotoi sensu lato-infected persons is reactive to B. burgdorferi antigens, we tested archived serum samples from area residents during 1991-2012. Of 639 samples from healthy persons, 25 were positive for B. miyamotoi sensu lato and 60 for B. burgdorferi. Samples from ≈10% of B. miyamotoi sensu lato-seropositive persons without a recent history of Lyme disease were seropositive for B. burgdorferi. Our results suggest that human B. miyamotoi sensu lato infection may be common in southern New England and that B. burgdorferi antibody testing is not an effective surrogate for detecting B. miyamotoi sensu lato infection. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 4 | 25% |
United States | 3 | 19% |
France | 1 | 6% |
Unknown | 8 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 13 | 81% |
Practitioners (doctors, other healthcare professionals) | 3 | 19% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 2% |
Australia | 1 | 1% |
Denmark | 1 | 1% |
Russia | 1 | 1% |
Japan | 1 | 1% |
Unknown | 83 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 22 | 25% |
Student > Ph. D. Student | 16 | 18% |
Student > Master | 10 | 11% |
Other | 9 | 10% |
Professor > Associate Professor | 8 | 9% |
Other | 11 | 12% |
Unknown | 13 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 21 | 24% |
Agricultural and Biological Sciences | 20 | 22% |
Biochemistry, Genetics and Molecular Biology | 9 | 10% |
Immunology and Microbiology | 7 | 8% |
Veterinary Science and Veterinary Medicine | 5 | 6% |
Other | 9 | 10% |
Unknown | 18 | 20% |