Title |
Increased Severity and Spread of Mycobacterium ulcerans, Southeastern Australia - Volume 24, Number 1—January 2018 - Emerging Infectious Diseases journal - CDC
|
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Published in |
Emerging Infectious Diseases, January 2018
|
DOI | 10.3201/eid2401.171070 |
Pubmed ID | |
Authors |
Alex Y.C. Tai, Eugene Athan, N. Deborah Friedman, Andrew Hughes, Aaron Walton, Daniel P. O’Brien |
Abstract |
Reported cases of Mycobacterium ulcerans disease (Buruli ulcer) have been increasing in southeastern Australia and spreading into new geographic areas. We analyzed 426 cases of M. ulcerans disease during January 1998-May 2017 in the established disease-endemic region of the Bellarine Peninsula and the emerging endemic region of the Mornington Peninsula. A total of 20.4% of cases-patients had severe disease. Over time, there has been an increase in the number of cases managed per year and the proportion associated with severe disease. Risk factors associated with severe disease included age, time period (range of years of diagnosis), and location of lesions over a joint. We highlight the changing epidemiology and pathogenicity of M. ulcerans disease in Australia. Further research, including genomic studies of emergent strains with increased pathogenicity, are urgently needed to improve the understanding of disease to facilitate implementation of effective public health measures to halt its spread. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Australia | 3 | 27% |
United Kingdom | 2 | 18% |
Unknown | 6 | 55% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 7 | 64% |
Practitioners (doctors, other healthcare professionals) | 2 | 18% |
Scientists | 1 | 9% |
Science communicators (journalists, bloggers, editors) | 1 | 9% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 52 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 8 | 15% |
Researcher | 8 | 15% |
Student > Bachelor | 6 | 12% |
Student > Postgraduate | 6 | 12% |
Student > Ph. D. Student | 4 | 8% |
Other | 7 | 13% |
Unknown | 13 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 10 | 19% |
Medicine and Dentistry | 10 | 19% |
Immunology and Microbiology | 6 | 12% |
Agricultural and Biological Sciences | 5 | 10% |
Nursing and Health Professions | 3 | 6% |
Other | 6 | 12% |
Unknown | 12 | 23% |