| Title |
Japanese Encephalitis Virus Transmitted Via Blood Transfusion, Hong Kong, China - Volume 24, Number 1—January 2018 - Emerging Infectious Diseases journal - CDC
|
|---|---|
| Published in |
Emerging Infectious Diseases, January 2018
|
| DOI | 10.3201/eid2401.171297 |
| Pubmed ID | |
| Authors |
Vincent C.C. Cheng, Siddharth Sridhar, Shuk-Ching Wong, Sally C.Y. Wong, Jasper F.W. Chan, Cyril C.Y. Yip, Chi-Hung Chau, Timmy W.K. Au, Yu-Yan Hwang, Carol S.W. Yau, Janice Y.C. Lo, Cheuk-Kwong Lee, Kwok-Yung Yuen |
| Abstract |
Japanese encephalitis virus (JEV) is a mosquitoborne virus endemic to China and Southeast Asia that causes severe encephalitis in <1% of infected persons. Transmission of JEV via blood transfusion has not been reported. We report transmission of JEV via blood donation products from an asymptomatic viremic donor to 2 immunocompromised recipients. One recipient on high-dose immunosuppressive drugs received JEV-positive packed red blood cells after a double lung transplant; severe encephalitis and a poor clinical outcome resulted. JEV RNA was detected in serum, cerebrospinal fluid, and bronchoalveolar lavage fluid specimens. The second recipient had leukemia and received platelets after undergoing chemotherapy. This patient was asymptomatic; JEV infection was confirmed in this person by IgM seroconversion. This study illustrates that, consistent with other pathogenic flaviviruses, JEV can be transmitted via blood products. Targeted donor screening and pathogen reduction technologies could be used to prevent transfusion-transmitted JEV infection in highly JEV-endemic areas. |
X Demographics
The data shown below were collected from the profiles of 13 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 38% |
| Georgia | 1 | 8% |
| Venezuela, Bolivarian Republic of | 1 | 8% |
| Brazil | 1 | 8% |
| Unknown | 5 | 38% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 46% |
| Scientists | 3 | 23% |
| Practitioners (doctors, other healthcare professionals) | 3 | 23% |
| Science communicators (journalists, bloggers, editors) | 1 | 8% |
Mendeley readers
The data shown below were compiled from readership statistics for 43 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 43 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 8 | 19% |
| Other | 4 | 9% |
| Student > Ph. D. Student | 3 | 7% |
| Student > Bachelor | 2 | 5% |
| Researcher | 2 | 5% |
| Other | 8 | 19% |
| Unknown | 16 | 37% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 12 | 28% |
| Biochemistry, Genetics and Molecular Biology | 5 | 12% |
| Agricultural and Biological Sciences | 2 | 5% |
| Nursing and Health Professions | 2 | 5% |
| Immunology and Microbiology | 2 | 5% |
| Other | 5 | 12% |
| Unknown | 15 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 September 2018.
All research outputs
#3,543,785
of 25,382,440 outputs
Outputs from Emerging Infectious Diseases
#3,397
of 9,718 outputs
Outputs of similar age
#76,248
of 451,258 outputs
Outputs of similar age from Emerging Infectious Diseases
#47
of 124 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 9,718 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 45.7. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 451,258 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 124 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.