| Title |
High Rate of MCR-1–Producing Escherichia coli and Klebsiella pneumoniae among Pigs, Portugal
|
|---|---|
| Published in |
Emerging Infectious Diseases, December 2017
|
| DOI | 10.3201/eid2312.170883 |
| Pubmed ID | |
| Authors |
Nicolas Kieffer, Marta Aires-de-Sousa, Patrice Nordmann, Laurent Poirel |
| Abstract |
The mcr-1 (mobile colistin resistance 1) gene, which encodes phosphoethanolamine transferase, has been recently identified as a source of acquired resistance to polymyxins in Escherichia coli. Using the SuperPolymyxin selective medium, we prospectively screened 100 pigs at 2 farms in Portugal for polymyxin-resistant Enterobacteriaceae and recovered 98 plasmid-mediated MCR-1-producing isolates. Most isolates corresponded to nonclonally related E. coli belonging to many sequence types; we also found 2 Klebsiella pneumoniae sequence types. The mcr-1 gene was carried on IncHI2 or IncP plasmid backbones. Our finding of a high rate of MCR-1 producers on 2 pig farms in Portugal highlights the diffusion of that colistin-resistance determinant at the farm level. The fact that the pigs received colistin as metaphylaxis in their feed during the 6 weeks before sampling suggests selective pressure. |
X Demographics
The data shown below were collected from the profiles of 16 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 2 | 13% |
| United Kingdom | 2 | 13% |
| United States | 2 | 13% |
| Spain | 1 | 6% |
| Unknown | 9 | 56% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 10 | 63% |
| Members of the public | 6 | 38% |
Mendeley readers
The data shown below were compiled from readership statistics for 97 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 97 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 17 | 18% |
| Student > Master | 16 | 16% |
| Student > Ph. D. Student | 10 | 10% |
| Student > Bachelor | 8 | 8% |
| Student > Postgraduate | 6 | 6% |
| Other | 10 | 10% |
| Unknown | 30 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 16 | 16% |
| Immunology and Microbiology | 10 | 10% |
| Veterinary Science and Veterinary Medicine | 9 | 9% |
| Agricultural and Biological Sciences | 8 | 8% |
| Medicine and Dentistry | 8 | 8% |
| Other | 13 | 13% |
| Unknown | 33 | 34% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 November 2017.
All research outputs
#3,449,129
of 23,975,876 outputs
Outputs from Emerging Infectious Diseases
#3,301
of 9,335 outputs
Outputs of similar age
#74,985
of 443,801 outputs
Outputs of similar age from Emerging Infectious Diseases
#75
of 159 outputs
Altmetric has tracked 23,975,876 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 9,335 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 44.3. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 443,801 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 159 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.