| Title |
Influence of Population Immunosuppression and Past Vaccination on Smallpox Reemergence - Volume 24, Number 4—April 2018 - Emerging Infectious Diseases journal - CDC
|
|---|---|
| Published in |
Emerging Infectious Diseases, April 2018
|
| DOI | 10.3201/eid2404.171233 |
| Pubmed ID | |
| Authors |
C. Raina MacIntyre, Valentina Costantino, Xin Chen, Eva Segelov, Abrar Ahmad Chughtai, Anthony Kelleher, Mohana Kunasekaran, John Michael Lane |
| Abstract |
We built a SEIR (susceptible, exposed, infected, recovered) model of smallpox transmission for New York, New York, USA, and Sydney, New South Wales, Australia, that accounted for age-specific population immunosuppression and residual vaccine immunity and conducted sensitivity analyses to estimate the effect these parameters might have on smallpox reemergence. At least 19% of New York's and 17% of Sydney's population are immunosuppressed. The highest smallpox infection rates were in persons 0-19 years of age, but the highest death rates were in those >45 years of age. Because of the low level of residual vaccine immunity, immunosuppression was more influential than vaccination on death and infection rates in our model. Despite widespread smallpox vaccination until 1980 in New York, smallpox outbreak severity appeared worse in New York than in Sydney. Immunosuppression is highly prevalent and should be considered in future smallpox outbreak models because excluding this factor probably underestimates death and infection rates. |
X Demographics
The data shown below were collected from the profiles of 183 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 20 | 11% |
| United States | 18 | 10% |
| Canada | 9 | 5% |
| United Kingdom | 7 | 4% |
| France | 3 | 2% |
| Côte d'Ivoire | 3 | 2% |
| Germany | 3 | 2% |
| Curaçao | 3 | 2% |
| Comoros | 2 | 1% |
| Other | 11 | 6% |
| Unknown | 104 | 57% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 153 | 84% |
| Scientists | 16 | 9% |
| Practitioners (doctors, other healthcare professionals) | 11 | 6% |
| Science communicators (journalists, bloggers, editors) | 3 | 2% |
Mendeley readers
The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 37 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 5 | 14% |
| Student > Ph. D. Student | 5 | 14% |
| Student > Bachelor | 4 | 11% |
| Researcher | 4 | 11% |
| Other | 3 | 8% |
| Other | 2 | 5% |
| Unknown | 14 | 38% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 7 | 19% |
| Environmental Science | 2 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 5% |
| Biochemistry, Genetics and Molecular Biology | 2 | 5% |
| Agricultural and Biological Sciences | 2 | 5% |
| Other | 7 | 19% |
| Unknown | 15 | 41% |
Attention Score in Context
This research output has an Altmetric Attention Score of 431. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 October 2023.
All research outputs
#67,514
of 25,770,491 outputs
Outputs from Emerging Infectious Diseases
#162
of 9,785 outputs
Outputs of similar age
#1,579
of 344,911 outputs
Outputs of similar age from Emerging Infectious Diseases
#1
of 115 outputs
Altmetric has tracked 25,770,491 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 9,785 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 46.3. This one has done particularly well, scoring higher than 98% of its peers.
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We're also able to compare this research output to 115 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.