| Title |
Cooperative Recognition of Internationally Disseminated Ceftriaxone-Resistant Neisseria gonorrhoeae Strain
|
|---|---|
| Published in |
Emerging Infectious Diseases, April 2018
|
| DOI | 10.3201/eid2404.171873 |
| Pubmed ID | |
| Authors |
Monica M. Lahra, Irene Martin, Walter Demczuk, Amy V. Jennison, Ken-Ichi Lee, Shu-Ichi Nakayama, Brigitte Lefebvre, Jean Longtin, Alison Ward, Michael R. Mulvey, Teodora Wi, Makoto Ohnishi, David Whiley |
| Abstract |
Ceftriaxone remains a first-line treatment for patients infected by Neisseria gonorrhoeae in most settings. We investigated the possible spread of a ceftriaxone-resistant FC428 N. gonorrhoeae clone in Japan after recent isolation of similar strains in Denmark (GK124) and Canada (47707). We report 2 instances of the FC428 clone in Australia in heterosexual men traveling from Asia. Our bioinformatic analyses included core single-nucleotide variation phylogeny and in silico molecular typing; phylogenetic analysis showed close genetic relatedness among all 5 isolates. Results showed multilocus sequence type 1903; N. gonorrhoeae sequence typing for antimicrobial resistance (NG-STAR) 233; and harboring of mosaic penA allele encoding alterations A311V and T483S (penA-60.001), associated with ceftriaxone resistance. Our results provide further evidence of international transmission of ceftriaxone-resistant N. gonorrhoeae. We recommend increasing awareness of international spread of this drug-resistant strain, strengthening surveillance to include identifying treatment failures and contacts, and strengthening international sharing of data. |
X Demographics
The data shown below were collected from the profiles of 35 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 7 | 20% |
| United States | 4 | 11% |
| Malaysia | 4 | 11% |
| Canada | 2 | 6% |
| South Africa | 1 | 3% |
| Sweden | 1 | 3% |
| Ecuador | 1 | 3% |
| Jersey | 1 | 3% |
| Australia | 1 | 3% |
| Other | 1 | 3% |
| Unknown | 12 | 34% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 19 | 54% |
| Scientists | 11 | 31% |
| Practitioners (doctors, other healthcare professionals) | 5 | 14% |
Mendeley readers
The data shown below were compiled from readership statistics for 87 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 87 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 14 | 16% |
| Student > Master | 10 | 11% |
| Student > Bachelor | 8 | 9% |
| Student > Ph. D. Student | 8 | 9% |
| Student > Doctoral Student | 7 | 8% |
| Other | 14 | 16% |
| Unknown | 26 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 18 | 21% |
| Biochemistry, Genetics and Molecular Biology | 14 | 16% |
| Immunology and Microbiology | 14 | 16% |
| Agricultural and Biological Sciences | 5 | 6% |
| Nursing and Health Professions | 2 | 2% |
| Other | 8 | 9% |
| Unknown | 26 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 25. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 November 2023.
All research outputs
#1,518,122
of 25,287,709 outputs
Outputs from Emerging Infectious Diseases
#1,725
of 9,717 outputs
Outputs of similar age
#32,606
of 336,350 outputs
Outputs of similar age from Emerging Infectious Diseases
#21
of 115 outputs
Altmetric has tracked 25,287,709 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 9,717 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 45.5. This one has done well, scoring higher than 82% of its peers.
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We're also able to compare this research output to 115 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 82% of its contemporaries.