Title |
Hepatitis E in Long-Term Travelers from the Netherlands to Subtropical and Tropical Countries, 2008–2011 - Volume 24, Number 6—June 2018 - Emerging Infectious Diseases journal - CDC
|
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Published in |
Emerging Infectious Diseases, June 2018
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DOI | 10.3201/eid2406.171513 |
Pubmed ID | |
Authors |
Floortje Elfrink, Femke W. Overbosch, Janke Schinkel, Gerrit Koen, Gerard J.B. Sonder |
Abstract |
Hepatitis E virus (HEV) is a common cause of acute viral hepatitis. Virus genotypes 1 and 2 infect humans in developing countries by the fecal-oral route. To assess attack rates and disease incidence for travelers, we prospectively studied 604 long-term travelers to subtropical and tropical countries. Participants donated blood samples pretravel and posttravel and kept a diary. A total of 89/604 (15%) pretravel samples were positive for HEV IgG by ELISA, suggesting previous HEV infection. Seroconversion for HEV was found for 19/515 travelers (attack rate 3.7%, incidence 1.8 cases/1,000 person-weeks). We believe there is a substantial risk for acquiring HEV infection among long-term travelers. Although HEV infection does not seem to be a major problem in this healthy cohort, hygienic measures should be stressed in all pretravel health advice, particularly for pregnant women and immunocompromised travelers who are at risk for severe disease. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 33% |
Germany | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 67% |
Science communicators (journalists, bloggers, editors) | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 25 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 5 | 20% |
Student > Master | 4 | 16% |
Other | 2 | 8% |
Student > Bachelor | 2 | 8% |
Lecturer | 1 | 4% |
Other | 2 | 8% |
Unknown | 9 | 36% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 4 | 16% |
Biochemistry, Genetics and Molecular Biology | 2 | 8% |
Veterinary Science and Veterinary Medicine | 2 | 8% |
Nursing and Health Professions | 1 | 4% |
Computer Science | 1 | 4% |
Other | 3 | 12% |
Unknown | 12 | 48% |