Title |
Case Definition of Chronic Pulmonary Aspergillosis in Resource-Constrained Settings - Volume 24, Number 8—August 2018 - Emerging Infectious Diseases journal - CDC
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Published in |
Emerging Infectious Diseases, August 2018
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DOI | 10.3201/eid2408.171312 |
Pubmed ID | |
Authors |
David W. Denning, Iain D. Page, Jeremiah Chakaya, Kauser Jabeen, Cecilia M. Jude, Muriel Cornet, Ana Alastruey-Izquierdo, Felix Bongomin, Paul Bowyer, Arunaloke Chakrabarti, Sara Gago, John Guto, Bruno Hochhegger, Martin Hoenigl, Muhammad Irfan, Nicholas Irurhe, Koichi Izumikawa, Bruce Kirenga, Veronica Manduku, Samihah Moazam, Rita O. Oladele, Malcolm D. Richardson, Juan Luis Rodriguez Tudela, Anna Rozaliyani, Helmut J.F. Salzer, Richard Sawyer, Nasilele F. Simukulwa, Alena Skrahina, Charlotte Sriruttan, Findra Setianingrum, Bayu A.P. Wilopo, Donald C. Cole, Haileyesus Getahun |
Abstract |
Chronic pulmonary aspergillosis (CPA) is a recognized complication of pulmonary tuberculosis (TB). In 2015, the World Health Organization reported 2.2 million new cases of nonbacteriologically confirmed pulmonary TB; some of these patients probably had undiagnosed CPA. In October 2016, the Global Action Fund for Fungal Infections convened an international expert panel to develop a case definition of CPA for resource-constrained settings. This panel defined CPA as illness for >3 months and all of the following: 1) weight loss, persistent cough, and/or hemoptysis; 2) chest images showing progressive cavitary infiltrates and/or a fungal ball and/or pericavitary fibrosis or infiltrates or pleural thickening; and 3) a positive Aspergillus IgG assay result or other evidence of Aspergillus infection. The proposed definition will facilitate advancements in research, practice, and policy in lower- and middle-income countries as well as in resource-constrained settings. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 3 | 14% |
Switzerland | 3 | 14% |
South Africa | 1 | 5% |
United States | 1 | 5% |
Uganda | 1 | 5% |
Guatemala | 1 | 5% |
Saudi Arabia | 1 | 5% |
Unknown | 10 | 48% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 13 | 62% |
Scientists | 5 | 24% |
Practitioners (doctors, other healthcare professionals) | 3 | 14% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 150 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 18 | 12% |
Researcher | 12 | 8% |
Student > Ph. D. Student | 9 | 6% |
Other | 8 | 5% |
Student > Postgraduate | 8 | 5% |
Other | 32 | 21% |
Unknown | 63 | 42% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 41 | 27% |
Immunology and Microbiology | 14 | 9% |
Biochemistry, Genetics and Molecular Biology | 8 | 5% |
Agricultural and Biological Sciences | 4 | 3% |
Computer Science | 3 | 2% |
Other | 16 | 11% |
Unknown | 64 | 43% |