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Major milestones in translational oncology

Overview of attention for article published in BMC Medicine, July 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)

Mentioned by

blogs
1 blog
twitter
13 tweeters
facebook
1 Facebook page

Citations

dimensions_citation
8 Dimensions

Readers on

mendeley
72 Mendeley
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Title
Major milestones in translational oncology
Published in
BMC Medicine, July 2016
DOI 10.1186/s12916-016-0654-y
Pubmed ID
Authors

Tommaso A. Dragani, Antoni Castells, Vathany Kulasingam, Eleftherios P. Diamandis, Helena Earl, Wade T. Iams, Christine M. Lovly, J. P. Michiel Sedelaar, Jack A. Schalken

Abstract

Translational oncology represents a bridge between basic research and clinical practice in cancer medicine. Today, translational research in oncology benefits from an abundance of knowledge resulting from genome-scale studies regarding the molecular pathways involved in tumorigenesis. In this Forum article, we highlight the state of the art of translational oncology in five major cancer types. We illustrate the use of molecular profiling to subtype colorectal cancer for both diagnosis and treatment, and summarize the results of a nationwide screening program for ovarian cancer based on detection of a tumor biomarker in serum. Additionally, we discuss how circulating tumor DNA can be assayed to safely monitor breast cancer over the course of treatment, and report on how therapy with immune checkpoint inhibitors is proving effective in advanced lung cancer. Finally, we summarize efforts to use molecular profiling of prostate cancer biopsy specimens to support treatment decisions. Despite encouraging early successes, we cannot disregard the complex genetics of individual susceptibility to cancer nor the enormous complexity of the somatic changes observed in tumors, which urge particular attention to the development of personalized therapies.

Twitter Demographics

The data shown below were collected from the profiles of 13 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Denmark 1 1%
Italy 1 1%
Unknown 70 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 15 21%
Student > Ph. D. Student 10 14%
Student > Master 9 13%
Other 8 11%
Student > Doctoral Student 7 10%
Other 14 19%
Unknown 9 13%
Readers by discipline Count As %
Medicine and Dentistry 23 32%
Biochemistry, Genetics and Molecular Biology 11 15%
Agricultural and Biological Sciences 7 10%
Nursing and Health Professions 5 7%
Pharmacology, Toxicology and Pharmaceutical Science 3 4%
Other 9 13%
Unknown 14 19%

Attention Score in Context

This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 August 2016.
All research outputs
#1,086,244
of 13,560,184 outputs
Outputs from BMC Medicine
#863
of 2,149 outputs
Outputs of similar age
#30,002
of 263,169 outputs
Outputs of similar age from BMC Medicine
#1
of 1 outputs
Altmetric has tracked 13,560,184 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,149 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 34.9. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 263,169 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them