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Antimicrobial nodule-specific cysteine-rich peptides disturb the integrity of bacterial outer and inner membranes and cause loss of membrane potential

Overview of attention for article published in Annals of Clinical Microbiology and Antimicrobials, July 2016
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Title
Antimicrobial nodule-specific cysteine-rich peptides disturb the integrity of bacterial outer and inner membranes and cause loss of membrane potential
Published in
Annals of Clinical Microbiology and Antimicrobials, July 2016
DOI 10.1186/s12941-016-0159-8
Pubmed ID
Authors

Kata R. Mikuláss, Krisztina Nagy, Balázs Bogos, Zsolt Szegletes, Etelka Kovács, Attila Farkas, György Váró, Éva Kondorosi, Attila Kereszt

Abstract

Certain legume plants produce a plethora of AMP-like peptides in their symbiotic cells. The cationic subgroup of the nodule-specific cysteine-rich (NCR) peptides has potent antimicrobial activity against gram-negative and gram-positive bacteria as well as unicellular and filamentous fungi. It was shown by scanning and atomic force microscopies that the cationic peptides NCR335, NCR247 and Polymyxin B (PMB) affect differentially on the surfaces of Sinorhizobium meliloti bacteria. Similarly to PMB, both NCR peptides caused damages of the outer and inner membranes but at different extent and resulted in the loss of membrane potential that could be the primary reason of their antimicrobial activity. The primary reason for bacterial cell death upon treatment with cationic NCR peptides is the loss of membrane potential.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 59 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 24%
Researcher 10 17%
Student > Bachelor 7 12%
Student > Master 6 10%
Other 3 5%
Other 4 7%
Unknown 15 25%
Readers by discipline Count As %
Agricultural and Biological Sciences 23 39%
Biochemistry, Genetics and Molecular Biology 14 24%
Unspecified 1 2%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Chemical Engineering 1 2%
Other 3 5%
Unknown 16 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 September 2016.
All research outputs
#13,986,187
of 22,881,964 outputs
Outputs from Annals of Clinical Microbiology and Antimicrobials
#265
of 609 outputs
Outputs of similar age
#208,876
of 365,664 outputs
Outputs of similar age from Annals of Clinical Microbiology and Antimicrobials
#5
of 7 outputs
Altmetric has tracked 22,881,964 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 609 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one has gotten more attention than average, scoring higher than 53% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 365,664 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.