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Are low birth weight neonates at risk for suboptimal renal growth and function during infancy?

Overview of attention for article published in BMC Nephrology, July 2016
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Title
Are low birth weight neonates at risk for suboptimal renal growth and function during infancy?
Published in
BMC Nephrology, July 2016
DOI 10.1186/s12882-016-0314-7
Pubmed ID
Authors

A. Iyengar, S. Nesargi, A. George, N. Sinha, S. Selvam, V. A. Luyckx

Abstract

To assess the renal growth and function of neonates during infancy in relation to birth weight and gestational age. A longitudinal study was conducted at a tertiary hospital in South India from June 2010 to August 2014. Low birth weight neonates (LBW) were further sub-classified based on gestational age and compared with normal birth weight (NBW) full term neonates at birth, 6 months and 18-24months of age. The renal volume was measured by ultrasound and renal function by Cystatin C- derived glomerular filtration rate (CysGFR) at the three time points during the dynamic phase of renal maturation in infancy. We recruited 100 LBW and 66 NBW term neonates. Thirty five percent of the LBW neonates were SGA. Among the AGA neonates, 39 % were LBW neonates. The mean height and weight of the LBW neonates were significantly lower compared to NBW neonates throughout infancy. The increment in kidney volume was in accordance with the change in body size, being lower in LBW compared to NBW infants. The combined kidney volume was significantly lower in LBW and SGA neonates across all three time points (p < 0.001). CysGFR in the LBW and SGA infants, despite having low kidney volumes, were comparable to the GFRs of NBW and AGA neonates at the end of infancy. This study highlights the fact that both birth weight and gestational age influence kidney growth and function in infancy. At the end of infancy, despite a significant difference in kidney volumes and age at last follow up, the glomerular filtration rate was comparable between LBW and NBW infants. Though not statistically significant, there was a trend towards higher urine microalbumin in LBW compared to NBW in infancy.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 71 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 9 13%
Researcher 8 11%
Student > Master 8 11%
Student > Ph. D. Student 6 8%
Student > Doctoral Student 4 6%
Other 13 18%
Unknown 23 32%
Readers by discipline Count As %
Medicine and Dentistry 25 35%
Nursing and Health Professions 8 11%
Biochemistry, Genetics and Molecular Biology 2 3%
Sports and Recreations 2 3%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Other 8 11%
Unknown 24 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 August 2016.
All research outputs
#14,205,997
of 22,881,964 outputs
Outputs from BMC Nephrology
#1,208
of 2,480 outputs
Outputs of similar age
#213,155
of 365,307 outputs
Outputs of similar age from BMC Nephrology
#29
of 51 outputs
Altmetric has tracked 22,881,964 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,480 research outputs from this source. They receive a mean Attention Score of 4.7. This one has gotten more attention than average, scoring higher than 50% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 365,307 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 51 others from the same source and published within six weeks on either side of this one. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.