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Kynurenine and Serotonin Pathways

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Cover of 'Kynurenine and Serotonin Pathways'

Table of Contents

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    Book Overview
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    Chapter 1 Retro-, Intro- and Perspectives of Trypto-Fun
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    Chapter 2 Tryptophan and Related Alkaloids
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    Chapter 3 Stability of Tryptophan in Peptides Against Oxidation and Irradiation
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    Chapter 4 Mass Spectrometric Determinations of Tryptophan and its Metabolites
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    Chapter 5 Signal-to-Noise Optimization of HPLC-Fluorometric Systems and their Application to the Analysis of Indoles
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    Chapter 6 Brain Indole Metabolism Assessed Using in Vivo Dialysis
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    Chapter 7 Sub-Picogram Determination of Serotonin Using HPLC with Electrochemical Detection for Microdialysis Studies of Serotonin Release
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    Chapter 8 Autoradiographic Measurement of the Rate of Serotonin Synthesis in the Rat Brain
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    Chapter 9 Autoradiographic Studies of 5HT2 Receptors
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    Chapter 10 Ambivalence on the Multiplicity of Mammalian Aromatic L-Amino Acid Decarboxylase
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    Chapter 11 Interrelationships of DNA Cycles and Melatonin Synthesis
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    Chapter 12 Regulation of Melatonin Synthesis in the Ovine Pineal Gland
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    Chapter 13 Melatonin Synthesis: Multiplicity of Regulation
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    Chapter 14 The Role of Tryptophan and Kynurenine Transport in the Catabolism of Tryptophan Through Indoleamine 2,3-Dioxygenase
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    Chapter 15 Kynureninase and Kynurenine 3-Hydroxylase in Mammalian Tissues
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    Chapter 16 Relationships Between Pteridine Synthesis and Tryptophan Degradation
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    Chapter 17 Quinolinic Acid and Kynurenic Acid in the Mammalian Brain
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    Chapter 18 Kynurenate Forming Enzymes in Liver, Kidney and Brain
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    Chapter 19 Regulation of Pyridine Nucleotide Coenzyme Metabolism
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    Chapter 20 Serotonin: Its Role and Receptors in Enteric Neurotransmission
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    Chapter 21 Mechanisms of Serotonergic Affect Control
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    Chapter 22 Neuroendocrine Responses to L-Tryptophan as an Index of Brain Serotonin Function: Effect of Weight Loss
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    Chapter 23 Melatonin Receptors in the Central Nervous System
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    Chapter 24 Melatonin Interaction with the Benzodiazepine-GABA Receptor Complex in the CNS
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    Chapter 25 Effects of Tryptophan 2,3-Dioxygenase Inhibitors in the Rat
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    Chapter 26 Bidirectional Relationships Between Tryptophan and Social Behavior in Vervet Monkeys
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    Chapter 27 The Regulation of Brain Kynurenic Acid Content: Focus on Indole-3-Pyruvic Acid
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    Chapter 28 Physiological Role of 3-Hydroxykynurenine and Xanthurenic Acid Upon Crustacean Molting
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    Chapter 29 Kynurenines in the Regulation of Behavior in Insects
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    Chapter 30 Effects of Quinolinic and Kynurenic Acids on Central Neurons
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    Chapter 31 Behavioral Abnormalities in Rats after Single Treatment with Quinolinic Acid During Early Ontogenesis
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    Chapter 32 Tryptophan Nutrition and Metabolism: An Overview
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    Chapter 33 Comparison of Tryptophan Metabolism in Vivo and in Isolated Hepatocytes from Vitamin B6 Deficient Mice
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    Chapter 34 Effects of the Diet and other Metabolic Phenomena on Brain Tryptophan Uptake and Serotonin Synthesis
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    Chapter 35 Effects of Tryptophan and of 5-Hydroxytryptamine Receptor Subtype Agonists on Feeding
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    Chapter 36 The Role of Serotonin (5-HT) in Feeding Responses to Amino Acids
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    Chapter 37 Cardiovascular and Endocrine Properties of L-Tryptophan in Combination with Various Diets
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    Chapter 38 Acute Effects of Meals on Brain Tryptophan and Serotonin in Humans
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    Chapter 39 Implications of Interferon-Induced Tryptophan Catabolism in Cancer, Autoimmune Diseases and Aids
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    Chapter 40 Induction of Indoleamine 2,3-Dioxygenase in Tumor Cells Transplanted into Allogeneic Mouse: Interferon-γ is the Inducer
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    Chapter 41 Plasma Free 5HT, Plasma 5HIAA and Whole Blood 5HT in the Rat
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    Chapter 42 Effects of Clomipramine on Extracellular Serotonin in the Rat Frontal Cortex
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    Chapter 43 Tryptophan Metabolism in Senile Cataract Patients Assessed by High-Performance Liquid Chromatography
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    Chapter 44 The Effect of Aluminum on Rat Brain and Liver Quinolinic Acid Concentrations
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    Chapter 45 Kynurenine and Lipid Metabolism
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    Chapter 46 Content of Tryptophan in Human Hair
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    Chapter 47 Detection of a New Intermediate Product of Indolealkylamine Metabolism in the Brain
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    Chapter 48 The Excretion of N1-Methyl-2-Pyridone-5-Carboxylic Acid and Related Compounds in Human Subjects after Oral Administration of Nicotinic Acid, Trigonalline and N1-Methyl-2-Pyridone-5-Carboxylic Acid
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    Chapter 49 Stable Isotope-Labeled Tryptophan as a Precursor for Studying the Disposition of Quinolinic Acid in Rabbits
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    Chapter 50 Evidence for the Preferential Production of 3-Hydroxyanthranilic Acid from Anthranilic Acid in the Rat Brain
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    Chapter 51 Chronobiological Effects of L-Tryptophan in Humans: Influence on Melatonin Secretion
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    Chapter 52 Circadian Patterns of Salivary Melatonin and Urinary 6-Sulfatoxy-Melatonin before and after A 9 Hour Time-Shift
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    Chapter 53 Tryptophan Metabolism in Mice Infected with Schistosoma Mansoni
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    Chapter 54 Inhibition of Tryptophan → Niacin Metabolism by Dietary Leucine and by Leucine and 2-Oxo-isocaproate in vitro
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    Chapter 55 Induction of Indoleamine 2,3-Dioxygenase in Human Cells in Vitro
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    Chapter 56 Differential Effects of Estradiol and Hydrocortisone on Liver Tryptophan Pyrrolase in Rats of Various Ages
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    Chapter 57 Indole-3-Pyruvic Acid as a Direct Precursor of Kynurenic Acid
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    Chapter 58 Tryptophan Metabolism in Healthy Subjects: Influence of Pyridoxine after Single or Repeated Administrations
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    Chapter 59 On Kynureninase Activity
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    Chapter 60 Rat Skin Tryptophan 2,3-Dioxygenase
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    Chapter 61 Kynurenine 3-Monooxygenase Activity of Rat Brain Mitochondria Determined by High Performance Liquid Chromatography with Electrochemical Detection
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    Chapter 62 Indolic and Kynurenine Pathway Metabolites of Tryptophan in Rat Brain: Effect of Precursor Availability on in Vivo Release
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    Chapter 63 Kinetic Properties of Human Liver Tryptophan Pyrrolase
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    Chapter 64 Interferon Type I and II Antagonism: A Novel Regulatory Mechanism of Indoleamine Dioxygenase Induction in Human Peripheral Blood Monocytes and Peritoneal Macrophages
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    Chapter 65 Quinolinic Acid Concentrations are Increased in Cerebrospinal Fluid of Rhesus Macaques (Macaca Mulatta) Naturally Infected with Simian Retrovirus Type
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    Chapter 66 Increased L-Tryptophan, 5-Hydroxyindoleacetic Acid, 3-Hydroxykynurenine and Quinolinic Acid Concentrations in Cerebral Cortex Following Systemic Endotoxin Administration
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    Chapter 67 Non-Competitive Inhibition of 3-Hydroxyanthranilate-3, 4-Dioxygenase by 4-Chloro-3-Hydroxyanthranilic Acid in Whole Brain of Rat
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    Chapter 68 Kynurenine-Pyruvate Aminotransferase in Rat Kidney and Brain
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    Chapter 69 Enzymatic Synthesis of Papiliochrome II
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    Chapter 70 4-Halo-3-Hydroxyanthranilates are Potent Inhibitors of 3-Hydroxyanthranilate Oxygenase in the Rat Brain in Vitro and in Vivo
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    Chapter 71 On the Disposition of De Novo Synthesized Quinolinic Acid in Rat Brain Tissue
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    Chapter 72 Brain-Specific Control of Kynurenic Acid Production by Depolarizing Agents
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    Chapter 73 Effects of 5-Hydroxytryptophan on Eating Behavior and Adherence to Dietary Prescriptions in Obese Adult Subjects
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    Chapter 74 The Involvement of Bulbospinal Serotonergic Neurons in the Effect of 5-Hydroxytryptophan on Alpha and Gamma Motoneurons
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    Chapter 75 Quinolinic Acid-Induced Decreases in Acetylcholine Release in the Rat Nucleus Basalis Magnocellularis
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    Chapter 76 The Role of Transaminations in the Pharmacological Effects of Indole-3-Pyruvic Acid
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    Chapter 77 Endocrine Response of Prolactin, Cortisol, and Growth Hormone to Low Dose Intravenous L-Tryptophan in Healthy Subjects During Day and Night
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    Chapter 78 Specific Binding of L-Tryptophan to Serum Albumin and its Function in Vivo
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    Chapter 79 Effects of L-Tryptophan on the Brainstem Indole and Catecholamine Metabolites in Spontaneously Hypertensive Rats
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    Chapter 80 Effects of Tryptophan on the Development of Deoxycorticosterone Acetate (DOCA)-Induced Hypertension in Rats
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    Chapter 81 Cytotoxicity of 3-Hydroxykynurenine: Implications for CNS Damage in Neonatal Vitamin B-6 Deficiency
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    Chapter 82 Pellagra, Mycotoxins and Tryptophan-Niacin Metabolism
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    Chapter 83 Levels of Non-Proteic Tryptophan in Milk and Soybean Formulas
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    Chapter 84 Characterization of L-Tryptophan Transport into Liver in Suckling Rats
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    Chapter 85 Efficiency of Exogenous Quinolinic Acid, A Metabolite of Tryptophan, as a Niacin Precursor in Rats
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    Chapter 86 Why does a Difference in Growth Rate between Rats of the Wistar and Sprague Dawley Strains Occur when a Niacin-Free and Tryptophan-Limiting Diet is Fed?
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    Chapter 87 Plasma Free 5HT and Platelet 5HT in Depression: Case-Control Studies and the Effect of Antidepressant Therapy
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    Chapter 88 Kynurenine and Mesangial-Proliferative Glomerulonephritis
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    Chapter 89 Impairment of Kynurenine Metabolism in Cardiovascular Disease
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    Chapter 90 Tryptophan and its Metabolites in a Family with Hartnup Disease
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    Chapter 91 Effect of Huntington’s and Alzheimer’s Diseases on the Transport of Nicotinic Acid or Nicotinamide Across the Human Blood-Brain Barrier
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    Chapter 92 Effects of Profound Insulin-Induced Hypoglycemia on Quinolinic Acid in Hippocampus and Plasma
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    Chapter 93 Brain and Cerebrospinal Fluid Quinolinic Acid Concentrations in Patients with Intractable Complex Partial Seizures
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    Chapter 94 Cerebrospinal Fluid Quinolinic Acid Concentrations are Increased in Acquired Immune Deficiency Syndrome
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    Chapter 95 Production of Quinolinic Acid and Kynurenic Acid by Human Glioma
Overall attention for this book and its chapters
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#19 of 3,562)
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (95th percentile)

Mentioned by

87 tweeters
2 Google+ users


21 Dimensions

Readers on

4 Mendeley
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Kynurenine and Serotonin Pathways
Published by
Advances in experimental medicine and biology, January 1991
DOI 10.1007/978-1-4684-5952-4
978-1-4684-5954-8, 978-1-4684-5952-4

Robert Schwarcz, Simon N. Young, Raymond R. Brown

Twitter Demographics

The data shown below were collected from the profiles of 87 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 4 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 4 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 75%
Student > Doctoral Student 1 25%
Readers by discipline Count As %
Chemistry 2 50%
Neuroscience 1 25%
Agricultural and Biological Sciences 1 25%

Attention Score in Context

This research output has an Altmetric Attention Score of 77. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 August 2016.
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So far Altmetric has tracked 3,562 research outputs from this source. They receive a mean Attention Score of 3.9. This one has done particularly well, scoring higher than 99% of its peers.
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We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.