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EphA5 and EphA6: regulation of neuronal and spine morphology

Overview of attention for article published in Cell & Bioscience, August 2016
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Title
EphA5 and EphA6: regulation of neuronal and spine morphology
Published in
Cell & Bioscience, August 2016
DOI 10.1186/s13578-016-0115-5
Pubmed ID
Authors

Gitanjali Das, Qili Yu, Ryan Hui, Kenneth Reuhl, Nicholas W. Gale, Renping Zhou

Abstract

The Eph family of receptor tyrosine kinases plays important roles in neural development. Previous studies have implicated Eph receptors and their ligands, the ephrins, in neuronal migration, axon bundling and guidance to specific targets, dendritic spine formation and neural plasticity. However, specific contributions of EphA5 and EphA6 receptors to the regulation of neuronal cell morphology have not been well studied. Here we show that deletion of EphA5 and EphA6 results in abnormal Golgi staining patterns of cells in the brain, and abnormal spine morphology. These observations suggest novel functions of these Eph receptors in the regulation of neuronal and spine structure in brain development and function.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 32 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 28%
Researcher 7 22%
Other 2 6%
Student > Bachelor 2 6%
Student > Master 2 6%
Other 2 6%
Unknown 8 25%
Readers by discipline Count As %
Neuroscience 9 28%
Agricultural and Biological Sciences 5 16%
Medicine and Dentistry 4 13%
Biochemistry, Genetics and Molecular Biology 3 9%
Immunology and Microbiology 1 3%
Other 2 6%
Unknown 8 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 August 2016.
All research outputs
#20,336,685
of 22,881,964 outputs
Outputs from Cell & Bioscience
#826
of 936 outputs
Outputs of similar age
#321,775
of 366,909 outputs
Outputs of similar age from Cell & Bioscience
#4
of 5 outputs
Altmetric has tracked 22,881,964 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 936 research outputs from this source. They receive a mean Attention Score of 3.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 366,909 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one.