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Caffeine discontinuation improves acute migraine treatment: a prospective clinic-based study

Overview of attention for article published in Journal of Headache & Pain, August 2016
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#7 of 1,024)
  • High Attention Score compared to outputs of the same age (98th percentile)

Mentioned by

news
22 news outlets
twitter
16 tweeters
facebook
3 Facebook pages

Citations

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15 Dimensions

Readers on

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79 Mendeley
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Title
Caffeine discontinuation improves acute migraine treatment: a prospective clinic-based study
Published in
Journal of Headache & Pain, August 2016
DOI 10.1186/s10194-016-0662-5
Pubmed ID
Authors

Mi Ji Lee, Hyun Ah Choi, Hanna Choi, Chin-Sang Chung

Abstract

Caffeine has both excitatory and vasoconstrictive effects on central nervous system. Caffeine use might be associated with development and chronification of migraine. We aimed to evaluate the effect of caffeine cessation on the acute treatment of migraine. We prospectively recruited migraine patients who consumed caffeine drinks daily and instructed them to discontinue their caffeine intake. Triptans were prescribed for acute treatment. Patients were followed up after at least two weeks after screening and evaluated the efficacy of acute treatment with the migraine assessment of current therapy (Migraine-ACT) questionnaire. Excellent efficacy was defined as Migraine-ACT score of 4. Chronic migraine, body mass index, allodynia, depression, anxiety, antiemetic use, and use of prophylactic medication were included in the multivariate analysis if the univariate p < 0.2. Among 108 patients included, 36 completely discontinued their caffeine intake (abstinence group). The efficacy of acute treatment was assessed at median 34.5 days (interquartile range, 28-89) after the screening. Twenty-six patients (72.2 %) in the abstinence group and 29 (40.3 %) in the non-abstinence group reported an excellent efficacy (p = 0.002). The abstinence group also showed a trend toward greater reduction of headache impact test-6 (HIT-6) scores (p = 0.085). Caffeine abstinence was independently associated with an excellent efficacy of acute treatment (multivariate odds ratio, 3.2; 95 % confidence interval, 1.2-8.4; p = 0.018) after controlling for covariates. Caffeine abstinence is associated with better efficacy of acute migraine treatment. Our uncontrolled study results encourage a further confirmatory study on this issue.

Twitter Demographics

The data shown below were collected from the profiles of 16 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 79 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 1 1%
Unknown 78 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 18 23%
Student > Master 16 20%
Researcher 6 8%
Student > Postgraduate 5 6%
Other 4 5%
Other 16 20%
Unknown 14 18%
Readers by discipline Count As %
Medicine and Dentistry 28 35%
Nursing and Health Professions 11 14%
Agricultural and Biological Sciences 4 5%
Environmental Science 3 4%
Biochemistry, Genetics and Molecular Biology 2 3%
Other 10 13%
Unknown 21 27%

Attention Score in Context

This research output has an Altmetric Attention Score of 190. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 August 2020.
All research outputs
#101,703
of 16,170,970 outputs
Outputs from Journal of Headache & Pain
#7
of 1,024 outputs
Outputs of similar age
#3,100
of 267,540 outputs
Outputs of similar age from Journal of Headache & Pain
#1
of 1 outputs
Altmetric has tracked 16,170,970 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,024 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.2. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 267,540 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them