Title |
I-131-Metaiodobenzylguanidine therapy with allogeneic cord blood stem cell transplantation for recurrent neuroblastoma
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Published in |
Italian Journal of Pediatrics, October 2012
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DOI | 10.1186/1824-7288-38-53 |
Pubmed ID | |
Authors |
Yuya Sato, Hidemitsu Kurosawa, Keitaro Fukushima, Mayuko Okuya, Susumu Hagisawa, Kenichi Sugita, Osamu Arisaka, Anri Inaki, Hiroshi Wakabayashi, Ayane Nakamura, Makoto Fukuoka, Daiki Kayano, Seigo Kinuya |
Abstract |
Iodine-131-metaiodiobenzylguanidine (131I-MIBG) therapy combined with allogeneic cord blood stem cell transplantation (SCT) was used to treat a 4-year-old girl with recurrent neuroblastoma. The patient experienced relapse 2 years after receiving first-line therapies, which included chemotherapy, surgical resection, irradiation, and autologous peripheral SCT. Although 131I-MIBG treatment did not achieve complete remission, the size of the tumor was reduced after treatment. Based on our findings, we suggest that 131I-MIBG treatment with myeloablative allogeneic SCT should be considered as first-line therapy for high-risk neuroblastoma patients when possible. |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 19 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Professor > Associate Professor | 6 | 32% |
Other | 3 | 16% |
Student > Postgraduate | 2 | 11% |
Researcher | 2 | 11% |
Student > Master | 2 | 11% |
Other | 3 | 16% |
Unknown | 1 | 5% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 13 | 68% |
Nursing and Health Professions | 1 | 5% |
Biochemistry, Genetics and Molecular Biology | 1 | 5% |
Psychology | 1 | 5% |
Chemistry | 1 | 5% |
Other | 0 | 0% |
Unknown | 2 | 11% |