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Maternal and Neonatal Morbidity and Mortality Among Pregnant Women With and Without COVID-19 Infection

Overview of attention for article published in JAMA Pediatrics, August 2021
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#5 of 3,417)
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (97th percentile)

Mentioned by

296 news outlets
19 blogs
4 policy sources
3363 tweeters
23 Facebook pages
2 Wikipedia pages
6 Redditors


836 Dimensions

Readers on

1323 Mendeley
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Maternal and Neonatal Morbidity and Mortality Among Pregnant Women With and Without COVID-19 Infection
Published in
JAMA Pediatrics, August 2021
DOI 10.1001/jamapediatrics.2021.1050
Pubmed ID

José Villar, Shabina Ariff, Robert B. Gunier, Ramachandran Thiruvengadam, Stephen Rauch, Alexey Kholin, Paola Roggero, Federico Prefumo, Marynéa Silva do Vale, Jorge Arturo Cardona-Perez, Nerea Maiz, Irene Cetin, Valeria Savasi, Philippe Deruelle, Sarah Rae Easter, Joanna Sichitiu, Constanza P. Soto Conti, Ernawati, Mohak Mhatre, Jagjit Singh Teji, Becky Liu, Carola Capelli, Manuela Oberto, Laura Salazar, Michael G. Gravett, Paolo Ivo Cavoretto, Vincent Bizor Nachinab, Hadiza Galadanci, Daniel Oros, Adejumoke Idowu Ayede, Loïc Sentilhes, Babagana Bako, Mónica Savorani, Hellas Cena, Perla K. García-May, Saturday Etuk, Roberto Casale, Sherief Abd-Elsalam, Satoru Ikenoue, Muhammad Baffah Aminu, Carmen Vecciarelli, Eduardo A. Duro, Mustapha Ado Usman, Yetunde John-Akinola, Ricardo Nieto, Enrico Ferrazzi, Zulfiqar A. Bhutta, Ana Langer, Stephen H. Kennedy, Aris T. Papageorghiou


Detailed information about the association of COVID-19 with outcomes in pregnant individuals compared with not-infected pregnant individuals is much needed. To evaluate the risks associated with COVID-19 in pregnancy on maternal and neonatal outcomes compared with not-infected, concomitant pregnant individuals. In this cohort study that took place from March to October 2020, involving 43 institutions in 18 countries, 2 unmatched, consecutive, not-infected women were concomitantly enrolled immediately after each infected woman was identified, at any stage of pregnancy or delivery, and at the same level of care to minimize bias. Women and neonates were followed up until hospital discharge. COVID-19 in pregnancy determined by laboratory confirmation of COVID-19 and/or radiological pulmonary findings or 2 or more predefined COVID-19 symptoms. The primary outcome measures were indices of (maternal and severe neonatal/perinatal) morbidity and mortality; the individual components of these indices were secondary outcomes. Models for these outcomes were adjusted for country, month entering study, maternal age, and history of morbidity. A total of 706 pregnant women with COVID-19 diagnosis and 1424 pregnant women without COVID-19 diagnosis were enrolled, all with broadly similar demographic characteristics (mean [SD] age, 30.2 [6.1] years). Overweight early in pregnancy occurred in 323 women (48.6%) with COVID-19 diagnosis and 554 women (40.2%) without. Women with COVID-19 diagnosis were at higher risk for preeclampsia/eclampsia (relative risk [RR], 1.76; 95% CI, 1.27-2.43), severe infections (RR, 3.38; 95% CI, 1.63-7.01), intensive care unit admission (RR, 5.04; 95% CI, 3.13-8.10), maternal mortality (RR, 22.3; 95% CI, 2.88-172), preterm birth (RR, 1.59; 95% CI, 1.30-1.94), medically indicated preterm birth (RR, 1.97; 95% CI, 1.56-2.51), severe neonatal morbidity index (RR, 2.66; 95% CI, 1.69-4.18), and severe perinatal morbidity and mortality index (RR, 2.14; 95% CI, 1.66-2.75). Fever and shortness of breath for any duration was associated with increased risk of severe maternal complications (RR, 2.56; 95% CI, 1.92-3.40) and neonatal complications (RR, 4.97; 95% CI, 2.11-11.69). Asymptomatic women with COVID-19 diagnosis remained at higher risk only for maternal morbidity (RR, 1.24; 95% CI, 1.00-1.54) and preeclampsia (RR, 1.63; 95% CI, 1.01-2.63). Among women who tested positive (98.1% by real-time polymerase chain reaction), 54 (13%) of their neonates tested positive. Cesarean delivery (RR, 2.15; 95% CI, 1.18-3.91) but not breastfeeding (RR, 1.10; 95% CI, 0.66-1.85) was associated with increased risk for neonatal test positivity. In this multinational cohort study, COVID-19 in pregnancy was associated with consistent and substantial increases in severe maternal morbidity and mortality and neonatal complications when pregnant women with and without COVID-19 diagnosis were compared. The findings should alert pregnant individuals and clinicians to implement strictly all the recommended COVID-19 preventive measures.

Twitter Demographics

Twitter Demographics

The data shown below were collected from the profiles of 3,363 tweeters who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 1,323 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 1323 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 138 10%
Student > Master 109 8%
Researcher 95 7%
Other 80 6%
Student > Ph. D. Student 74 6%
Other 242 18%
Unknown 585 44%
Readers by discipline Count As %
Medicine and Dentistry 379 29%
Nursing and Health Professions 112 8%
Biochemistry, Genetics and Molecular Biology 38 3%
Agricultural and Biological Sciences 26 2%
Social Sciences 26 2%
Other 116 9%
Unknown 626 47%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4573. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 September 2023.
All research outputs
of 24,514,423 outputs
Outputs from JAMA Pediatrics
of 3,417 outputs
Outputs of similar age
of 424,876 outputs
Outputs of similar age from JAMA Pediatrics
of 80 outputs
Altmetric has tracked 24,514,423 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,417 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 138.0. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 424,876 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 80 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.