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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Proteomics tools reveal startlingly high amounts of oxytocin in plasma and serum
|
|---|---|
| Published in |
Scientific Reports, August 2016
|
| DOI | 10.1038/srep31693 |
| Pubmed ID | |
| Authors |
Ole Kristian Brandtzaeg, Elin Johnsen, Hanne Roberg-Larsen, Knut Fredrik Seip, Evan L. MacLean, Laurence R. Gesquiere, Siri Leknes, Elsa Lundanes, Steven Ray Wilson |
| Abstract |
The neuropeptide oxytocin (OT) is associated with a plethora of social behaviors, and is a key topic at the intersection of psychology and biology. However, tools for measuring OT are still not fully developed. We describe a robust nano liquid chromatography-mass spectrometry (nanoLC-MS) platform for measuring the total amount of OT in human plasma/serum. OT binds strongly to plasma proteins, but a reduction/alkylation (R/A) procedure breaks this bond, enabling ample detection of total OT. The method (R/A + robust nanoLC-MS) was used to determine total OT plasma/serum levels to startlingly high concentrations (high pg/mL-ng/mL). Similar results were obtained when combining R/A and ELISA. Compared to measuring free OT, measuring total OT can have advantages in e.g. biomarker studies. |
X Demographics
The data shown below were collected from the profiles of 31 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 9 | 29% |
| Australia | 2 | 6% |
| Italy | 1 | 3% |
| Canada | 1 | 3% |
| Netherlands | 1 | 3% |
| India | 1 | 3% |
| Malaysia | 1 | 3% |
| United Kingdom | 1 | 3% |
| Norway | 1 | 3% |
| Other | 0 | 0% |
| Unknown | 13 | 42% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 19 | 61% |
| Scientists | 7 | 23% |
| Science communicators (journalists, bloggers, editors) | 3 | 10% |
| Practitioners (doctors, other healthcare professionals) | 2 | 6% |
Mendeley readers
The data shown below were compiled from readership statistics for 120 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | <1% |
| Hungary | 1 | <1% |
| United States | 1 | <1% |
| Norway | 1 | <1% |
| Unknown | 116 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 26 | 22% |
| Student > Ph. D. Student | 15 | 13% |
| Student > Doctoral Student | 12 | 10% |
| Student > Bachelor | 11 | 9% |
| Student > Master | 10 | 8% |
| Other | 19 | 16% |
| Unknown | 27 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 18 | 15% |
| Agricultural and Biological Sciences | 14 | 12% |
| Neuroscience | 10 | 8% |
| Medicine and Dentistry | 9 | 8% |
| Biochemistry, Genetics and Molecular Biology | 8 | 7% |
| Other | 23 | 19% |
| Unknown | 38 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 56. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 April 2024.
All research outputs
#777,688
of 25,918,104 outputs
Outputs from Scientific Reports
#8,406
of 142,856 outputs
Outputs of similar age
#14,227
of 341,737 outputs
Outputs of similar age from Scientific Reports
#241
of 3,707 outputs
Altmetric has tracked 25,918,104 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 142,856 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.8. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 341,737 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 3,707 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.