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Mendeley readers
Attention Score in Context
| Title |
L166P mutant DJ-1 promotes cell death by dissociating Bax from mitochondrial Bcl-XL
|
|---|---|
| Published in |
Molecular Neurodegeneration, August 2012
|
| DOI | 10.1186/1750-1326-7-40 |
| Pubmed ID | |
| Authors |
Haigang Ren, Kai Fu, Chenchen Mu, Xuechu Zhen, Guanghui Wang |
| Abstract |
Mutations or deletions in DJ-1/PARK7 gene are causative for recessive forms of early onset Parkinson's disease (PD). Wild-type DJ-1 has cytoprotective roles against cell death through multiple pathways. The most commonly studied mutant DJ-1(L166P) shifts its subcellular distribution to mitochondria and renders cells more susceptible to cell death under stress stimuli. We previously reported that wild-type DJ-1 binds to Bcl-XL and stabilizes it against ultraviolet B (UVB) irradiation-induced rapid degradation. However, the mechanisms by which mitochondrial DJ-1(L166P) promotes cell death under death stimuli are largely unknown. |
Mendeley readers
The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 32 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 7 | 22% |
| Student > Ph. D. Student | 5 | 16% |
| Student > Bachelor | 3 | 9% |
| Researcher | 3 | 9% |
| Student > Doctoral Student | 2 | 6% |
| Other | 3 | 9% |
| Unknown | 9 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 8 | 25% |
| Agricultural and Biological Sciences | 6 | 19% |
| Neuroscience | 4 | 13% |
| Medicine and Dentistry | 2 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
| Other | 2 | 6% |
| Unknown | 9 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 August 2012.
All research outputs
#20,172,971
of 22,685,926 outputs
Outputs from Molecular Neurodegeneration
#830
of 844 outputs
Outputs of similar age
#150,469
of 167,804 outputs
Outputs of similar age from Molecular Neurodegeneration
#9
of 11 outputs
Altmetric has tracked 22,685,926 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 844 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.1. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 167,804 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.