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Tertiary hypothyroidism in a dog

Overview of attention for article published in Irish Veterinary Journal, February 2007
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Title
Tertiary hypothyroidism in a dog
Published in
Irish Veterinary Journal, February 2007
DOI 10.1186/2046-0481-60-2-88
Pubmed ID
Authors

Robert E Shiel, Els Acke, Antonella Puggioni, Joseph P Cassidy, Carmel T Mooney

Abstract

: A nine-year-old male entire Labrador was diagnosed with pituitary dependent hyperadrenocorticism. Following seven months of successful mitotane therapy, the dog presented with marked weight gain, seborrhoea and alopecia. Routine clinicopathological analyses revealed marked hypercholesterolaemia. Serum total and free thyroxine (T4) concentrations were below their respective reference ranges. Serum thyroid stimulating hormone (cTSH) concentration was within reference range. TSH and thyrotropin releasing hormone (TRH) response tests revealed adequate stimulation of total T4 in both, and cTSH in the latter test. Magnetic resonance imaging revealed a mass arising from the pituitary fossa, with suprasellar extension. A diagnosis of tertiary hypothyroidism was made. Following four weeks of levothyroxine therapy, circulating cholesterol concentration had declined, weight loss had ensued and dermatological abnormalities had improved. Euthanasia was performed four months later due to the development of neurological signs. A highly infiltrative pituitary adenoma, with effacement of the overlying hypothalamus was identified on post mortem examination. Tertiary hypothyroidism has not been previously reported in dogs.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 50 98%

Demographic breakdown

Readers by professional status Count As %
Other 12 24%
Student > Postgraduate 7 14%
Student > Doctoral Student 6 12%
Student > Bachelor 5 10%
Researcher 3 6%
Other 9 18%
Unknown 9 18%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 19 37%
Medicine and Dentistry 14 27%
Agricultural and Biological Sciences 5 10%
Psychology 2 4%
Sports and Recreations 1 2%
Other 1 2%
Unknown 9 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 November 2012.
All research outputs
#19,944,091
of 25,373,627 outputs
Outputs from Irish Veterinary Journal
#171
of 257 outputs
Outputs of similar age
#159,994
of 168,727 outputs
Outputs of similar age from Irish Veterinary Journal
#3
of 3 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 257 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 168,727 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 4th percentile – i.e., 4% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.