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Improved Survival With Integration of Chinese Herbal Medicine Therapy in Patients With Acute Myeloid Leukemia: A Nationwide Population-Based Cohort Study

Overview of attention for article published in Integrative Cancer Therapies, August 2016
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (69th percentile)
  • Good Attention Score compared to outputs of the same age and source (66th percentile)

Mentioned by

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5 tweeters
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5 Facebook pages

Citations

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21 Dimensions

Readers on

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17 Mendeley
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Title
Improved Survival With Integration of Chinese Herbal Medicine Therapy in Patients With Acute Myeloid Leukemia: A Nationwide Population-Based Cohort Study
Published in
Integrative Cancer Therapies, August 2016
DOI 10.1177/1534735416664171
Pubmed ID
Authors

Tom Fleischer, Tung-Ti Chang, Jen-Huai Chiang, Mao-Feng Sun, Hung-Rong Yen

Abstract

Purpose Acute myeloid leukemia (AML) is the most deadly subtype of leukemia, and many patients with this disease seek other complementary therapies, one of which is Chinese medicine. We set out to provide reliable data regarding the benefit of Chinese herbal medicine (CHM) for AML patients, using mortality as the main outcome measure. We also characterized the herbal prescriptions of patients. Methods Using the Taiwanese National Health Insurance Research Database, we performed a nationwide population-based cohort study among AML patients from 1997 to 2010. The Cox regression model was used to adjust for comorbidities and other variables, and the hazard ratios (HRs) of CHM users and non-CHM users were compared. Results After 1:1 matching, 498 patients were included into the study. The HR of the CHM group was 0.41 (95% CI = 0.26-0.65; P = .0001) compared with the non-CHM group. This decrease in HR was also shown to be dose dependent (P < .001). The 3 single-herbs most commonly prescribed were Salvia miltiorrhiza (Dan Shen), Astragalus membranaceus (Huang Qi), and Spatholobus suberectus (Ji Xue Teng). The 3 mutli-herb products most commonly prescribed were Jia Wei Xiao Yao San, Gui Pi Tang, and Qi Ju Di Huang Wan. Conclusion Prospective controlled clinical data is still needed, however, this study provides real-world data regarding the benefit AML patients may have from CHM. This study suggests that all AML patients, regardless of age or other prognostic factors, may achieve longer survival times when receiving CHM in addition to standard therapy.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 1 6%
Unknown 16 94%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 4 24%
Student > Ph. D. Student 4 24%
Other 3 18%
Student > Doctoral Student 2 12%
Student > Master 2 12%
Other 1 6%
Unknown 1 6%
Readers by discipline Count As %
Medicine and Dentistry 5 29%
Pharmacology, Toxicology and Pharmaceutical Science 2 12%
Nursing and Health Professions 2 12%
Biochemistry, Genetics and Molecular Biology 2 12%
Psychology 1 6%
Other 2 12%
Unknown 3 18%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 May 2017.
All research outputs
#3,310,139
of 12,490,047 outputs
Outputs from Integrative Cancer Therapies
#144
of 472 outputs
Outputs of similar age
#78,179
of 262,033 outputs
Outputs of similar age from Integrative Cancer Therapies
#6
of 18 outputs
Altmetric has tracked 12,490,047 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 472 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.9. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 262,033 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.