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Anti-HBV efficacy of combined siRNAs targeting viral gene and heat shock cognate 70

Overview of attention for article published in Virology Journal, November 2012
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  • Above-average Attention Score compared to outputs of the same age and source (64th percentile)

Mentioned by

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2 X users
peer_reviews
1 peer review site

Citations

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11 Dimensions

Readers on

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19 Mendeley
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Title
Anti-HBV efficacy of combined siRNAs targeting viral gene and heat shock cognate 70
Published in
Virology Journal, November 2012
DOI 10.1186/1743-422x-9-275
Pubmed ID
Authors

Zhongqi Bian, An Xiao, Mingmei Cao, Mingqiu Liu, Shuang Liu, Ye Jiao, Weiyao Yan, Zhongtian Qi, Zhaoxin Zheng

Abstract

Hepatitis B virus (HBV) infection is a major health concern with more than two billion individuals currently infected worldwide. Because of the limited effectiveness of existing vaccines and drugs, development of novel antiviral strategies is urgently needed. Heat stress cognate 70 (Hsc70) is an ATP-binding protein of the heat stress protein 70 family. Hsc70 has been found to be required for HBV DNA replication. Here we report, for the first time, that combined siRNAs targeting viral gene and siHsc70 are highly effective in suppressing ongoing HBV expression and replication.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 19 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 26%
Researcher 3 16%
Student > Ph. D. Student 2 11%
Student > Bachelor 2 11%
Student > Doctoral Student 1 5%
Other 1 5%
Unknown 5 26%
Readers by discipline Count As %
Agricultural and Biological Sciences 4 21%
Medicine and Dentistry 3 16%
Psychology 2 11%
Mathematics 1 5%
Immunology and Microbiology 1 5%
Other 3 16%
Unknown 5 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 January 2015.
All research outputs
#14,476,441
of 24,417,958 outputs
Outputs from Virology Journal
#1,458
of 3,251 outputs
Outputs of similar age
#90,027
of 162,403 outputs
Outputs of similar age from Virology Journal
#32
of 87 outputs
Altmetric has tracked 24,417,958 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,251 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.0. This one has gotten more attention than average, scoring higher than 54% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 162,403 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 87 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.