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Is There Potential for Repurposing Statins as Novel Antimicrobials?

Overview of attention for article published in Antimicrobial Agents and Chemotherapy, September 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

Mentioned by

news
1 news outlet
twitter
15 tweeters
patent
3 patents

Citations

dimensions_citation
67 Dimensions

Readers on

mendeley
82 Mendeley
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Title
Is There Potential for Repurposing Statins as Novel Antimicrobials?
Published in
Antimicrobial Agents and Chemotherapy, September 2016
DOI 10.1128/aac.00192-16
Pubmed ID
Authors

Emma Hennessy, Claire Adams, F. Jerry Reen, Fergal O'Gara

Abstract

Statins are a class of pharmaceutical widely used to treat high serum cholesterol. In addition, statins have so-called "pleiotropic effects", which include the reduction of inflammation, immunomodulation, and anti-microbial effects. An increasing number of studies are emerging which detail the attenuation of bacterial growth and in vitro and in vivo virulence by statin treatment. In this review, we describe the current information available surrounding the effects of statins on bacterial infections, and provide insight regarding the potential use of these compounds as anti-microbial therapeutic agents.

Twitter Demographics

The data shown below were collected from the profiles of 15 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 82 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 82 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 13 16%
Student > Ph. D. Student 10 12%
Researcher 9 11%
Student > Bachelor 8 10%
Other 6 7%
Other 19 23%
Unknown 17 21%
Readers by discipline Count As %
Medicine and Dentistry 19 23%
Immunology and Microbiology 11 13%
Biochemistry, Genetics and Molecular Biology 10 12%
Pharmacology, Toxicology and Pharmaceutical Science 7 9%
Agricultural and Biological Sciences 4 5%
Other 7 9%
Unknown 24 29%

Attention Score in Context

This research output has an Altmetric Attention Score of 25. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 June 2020.
All research outputs
#1,098,036
of 19,584,195 outputs
Outputs from Antimicrobial Agents and Chemotherapy
#435
of 14,216 outputs
Outputs of similar age
#22,547
of 282,753 outputs
Outputs of similar age from Antimicrobial Agents and Chemotherapy
#25
of 270 outputs
Altmetric has tracked 19,584,195 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 14,216 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.5. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 282,753 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 270 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.