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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Development of Light‐Activated CRISPR Using Guide RNAs with Photocleavable Protectors
|
|---|---|
| Published in |
Angewandte Chemie. International Edition, August 2016
|
| DOI | 10.1002/anie.201606123 |
| Pubmed ID | |
| Authors |
Piyush K. Jain, Vyas Ramanan, Arnout G. Schepers, Nisha S. Dalvie, Apekshya Panda, Heather E. Fleming, Sangeeta N. Bhatia |
| Abstract |
The ability to remotely trigger CRISPR/Cas9 activity would enable new strategies to study cellular events with greater precision and complexity. In this work, we have developed a method to photocage the activity of the guide RNA called "CRISPR-plus" (CRISPR-precise light-mediated unveiling of sgRNAs). The photoactivation capability of our CRISPR-plus method is compatible with the simultaneous targeting of multiple DNA sequences and supports numerous modifications that can enable guide RNA labeling for use in imaging and mechanistic investigations. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 2 | 67% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 2 | 67% |
| Members of the public | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 187 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Unknown | 186 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 46 | 25% |
| Researcher | 33 | 18% |
| Student > Master | 27 | 14% |
| Student > Bachelor | 17 | 9% |
| Student > Doctoral Student | 15 | 8% |
| Other | 23 | 12% |
| Unknown | 26 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 53 | 28% |
| Chemistry | 35 | 19% |
| Agricultural and Biological Sciences | 33 | 18% |
| Medicine and Dentistry | 11 | 6% |
| Engineering | 11 | 6% |
| Other | 11 | 6% |
| Unknown | 33 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 270. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 January 2024.
All research outputs
#133,145
of 25,394,764 outputs
Outputs from Angewandte Chemie. International Edition
#22
of 50,044 outputs
Outputs of similar age
#2,734
of 352,765 outputs
Outputs of similar age from Angewandte Chemie. International Edition
#1
of 758 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 50,044 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.8. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 352,765 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 758 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.