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Retinal Degenerative Diseases

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Cover of 'Retinal Degenerative Diseases'

Table of Contents

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    Book Overview
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    Chapter 1 Genetic factors modifying clinical expression of autosomal dominant RP.
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    Chapter 2 Disease-associated variants of the rod-derived cone viability factor (RdCVF) in Leber congenital amaurosis. Rod-derived cone viability variants in LCA.
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    Chapter 3 Leber Congenital Amaurosis: Survey of the Genetic Heterogeneity, Refinement of the Clinical Definition and Phenotype-Genotype Correlations as a Strategy for Molecular Diagnosis
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    Chapter 4 A first locus for isolated autosomal recessive optic atrophy (ROA1) maps to chromosome 8q21-q22.
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    Chapter 5 RCC1-like domain and ORF15: essentials in RPGR gene.
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    Chapter 6 Choroidal neovascularization in patients with adult-onset foveomacular dystrophy caused by mutations in the RDS/peripherin gene.
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    Chapter 7 Biochemical characterisation of the C1QTNF5 gene associated with late-onset retinal degeneration. A genetic model of age-related macular degeneration.
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    Chapter 8 Bietti crystalline corneoretinal dystrophy associated with CYP4V2 gene mutations.
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    Chapter 9 Fundus appearance of choroideremia using optical coherence tomograpy.
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    Chapter 10 A2E, a fluorophore of RPE lipofuscin, can destabilize membrane.
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    Chapter 11 Amino-retinoid compounds in the human retinal pigment epithelium.
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    Chapter 12 Annexins in Bruch’s Memberane and Drusen
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    Chapter 13 Molecular mechanisms of photoreceptor degeneration in RP caused by IMPDH1 mutations.
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    Chapter 14 Biochemical Function of the LCA Linked Protien, Aryl Hydrocarbon Receptor Interacting Protein Like-1 (AIPL1)
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    Chapter 15 Characterization of mouse mutants with abnormal RPE cells.
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    Chapter 16 Rod and Cone Pigment Regeneration in RPE65 -/- Mice
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    Chapter 17 Initial Observations of Key Features of Age-Related Macular Degeneration in APOE Targeted Replacement Mice
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    Chapter 18 Altered rhythm of photoreceptor outer segment phagocytosis in beta5 integrin knockout mice.
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    Chapter 19 Light/dark translocation of alphatransducin in mouse photoreceptor cells expressing G90D mutant opsin.
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    Chapter 20 Slowed photoresponse recovery and age-related degeneration in cones lacking G protein-coupled receptor kinase 1.
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    Chapter 21 Transgenic animal studies of human retinal disease caused by mutations in peripherin/rds.
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    Chapter 22 Transgenic Expression of Leukemia Inhibitory Factor Inhibits Both Rod and Cone Gene Expression
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    Chapter 23 A role for bHLH transcription factors in retinal degeneration and dysfunction.
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    Chapter 24 Characterisation of a model for retinal neovascularisation. VEGF model characterisation.
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    Chapter 25 A two-alternative, forced choice method for assessing mouse vision.
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    Chapter 26 Conditional gene knockout system in cone photoreceptors.
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    Chapter 27 Regulation of tight junction proteins in cultured retinal pigment epithelial cells and in VEGF overexpressing transgenic mouse retinas.
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    Chapter 28 Pathological heterogeneity of vasoproliferative retinopathy in transgenic mice overexpressing vascular endothelial growth factor in photoreceptors.
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    Chapter 29 Laser photocoagulation: ocular research and therapy in diabetic retinopathy.
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    Chapter 30 Applying transgenic zebrafish technology to study the retina.
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    Chapter 31 Bmi1 Loss Delays Photoreceptor Degeneration in Rd1 Mice
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    Chapter 32 Transcriptional and post-transcriptional regulation of the rod cGMP-phosphodiesterase beta-subunit gene. Recent advances and current concepts.
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    Chapter 33 Down-regulation of rhodopsin gene expression by AAV-vectored short interfering RNA.
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    Chapter 34 Assessing the Efficacy of Gene Therapy in Rpe65 -/- Mice Using Photoentrainment of Circadian Phythm
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    Chapter 35 Lentiviral Vectors Containing a Retinal Pigment Epithelium Specific Promoter for Leber Congenital Amaurosis Gene Therapy
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    Chapter 36 Gene delivery to the retina using lentiviral vectors.
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    Chapter 37 Potential Use of Cellular Promoter(s) to Target RPE in AAV-Mediated Delivery
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    Chapter 38 Cytokine-induced retinal degeneration: role of suppressors of cytokine signaling (SOCS) proteins in protection of the neuroretina.
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    Chapter 39 Disease mechanisms and gene therapy in a mouse model for X-linked retinoschisis.
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    Chapter 40 Molecular mechanisms of neuroprotection in the eye.
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    Chapter 41 Retinal damage caused by photodynamic therapy can be reduced using BDNF.
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    Chapter 42 Controlling Vascular Endothelial Growth Factor: Therapies for Ocular Diseases Associated with Nevascularization
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    Chapter 43 Intravitreal injection of triamcinolone acetonide for macular edema due to retinitis pigmentosa and other retinal diseases.
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    Chapter 44 Cone survival: identification of RdCVF.
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    Chapter 45 Neuroprotection of photoreceptors in the RCS rat after implantation of a subretinal implant in the superior or inferior retina.
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    Chapter 46 Glutamate transport modulation: a possible role in retinal neuroprotection.
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    Chapter 47 Activation of cell survival signals in the goldfish retinal ganglion cells after optic nerve injury.
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    Chapter 48 Roles and interactions of usher 1 proteins in the outer retina.
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    Chapter 49 Molecular analysis of the supramolecular usher protein complex in the retina. Harmonin as the key protein of the Usher syndrome.
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    Chapter 50 Limited neural differentiation of retinal pigment epithelium.
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    Chapter 51 Retinal pigment epithelial cells from thermally responsive polymer-grafted surface reduce apoptosis.
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    Chapter 52 Retinal Transpilantation
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    Chapter 53 Microarray Analysis Reveals Retinal Stem Cell Characteristics of the Adult Human Eye
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    Chapter 54 Using Stem Cells to Repair the Degenerate Retina
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    Chapter 55 Retinal Degenerative Diseases
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    Chapter 56 Retinal ganglion cell remodelling in experimental glaucoma.
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    Chapter 57 Neural plasticity revealed by light-induced photoreceptor lesions.
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    Chapter 58 Factors underlying circadian dependent susceptibility to light induced retinal damage.
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    Chapter 59 Space flight environment induces degeneration in the retina of rat neonates.
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    Chapter 60 Toxicity of hyperoxia to the retina: evidence from the mouse.
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    Chapter 61 Treatment with carbonic anhydrase inhibitors depresses electroretinogram responsiveness in mice.
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    Chapter 62 Injury-induced retinal ganglion cell loss in the neonatal rat retina.
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    Chapter 63 Arrestin translocation in rod photoreceptors.
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    Chapter 64 Binding of N-Retinylidene-Pe to BACA4 and a Model for its Transport Across Membranes
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    Chapter 65 The chaperone function of the LCA protein AIPL1. AIPL1 chaperone function.
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    Chapter 66 CRALBP ligand and protein interactions.
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    Chapter 67 Functional study of photoreceptor PDEdelta.
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    Chapter 68 Localization of the insulin receptor and phosphoinositide 3-kinase in detergent-resistant membrane rafts of rod photoreceptor outer segments.
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    Chapter 69 MerTK activation during RPE phagocytosis in vivo requires alphaVbeta5 integrin.
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    Chapter 70 Photoreceptor retinol dehydrogenases. An attempt to characterize the function of Rdh11.
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    Chapter 71 Pigment epithelium-derived growth factor inhibits fetal bovine serum stimulated vascular endothelial growth factor synthesis in cultured human retinal pigment epithelial cells.
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    Chapter 72 The retinal pigment epithelium apical microvilli and retinal function.
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    Chapter 73 Upregulation of transglutaminase in the goldfish retina during optic nerve regeneration.
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    Chapter 74 Survival signaling in retinal pigment epithelial cells in response to oxidative stress: significance in retinal degenerations.
Overall attention for this book and its chapters
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Retinal Degenerative Diseases
Published by
Springer US, January 2006
DOI 10.1007/0-387-32442-9
978-0-387-28464-4, 978-0-387-32442-5

Anderson, Robert E, Hollyfield, Joe G, LaVail, Matthew M


Joe G. Hollyfield, Robert E. Anderson, Matthew M. LaVail

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 11 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 2 18%
Student > Bachelor 2 18%
Professor 1 9%
Student > Ph. D. Student 1 9%
Student > Doctoral Student 1 9%
Other 0 0%
Unknown 4 36%
Readers by discipline Count As %
Business, Management and Accounting 2 18%
Pharmacology, Toxicology and Pharmaceutical Science 2 18%
Environmental Science 1 9%
Agricultural and Biological Sciences 1 9%
Physics and Astronomy 1 9%
Other 0 0%
Unknown 4 36%