#mTOR has many important homeostatic functions—but its dysregulated activation is pathogenic in #neurodegeneration: —inhibiting insulin signaling —inhibiting autophagy & removal of Aβ and ptau aggregates —cerebrovascular dysfunction Mol Neurodegener
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'Mammalian/mechanistic target of #rapamycin (mTOR) complexes in #neurodegeneration' @TuftsMedicalCtr https://t.co/1R4qqgJmeJ https://t.co/hOMJJJfwG9
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RT @agingdoc1: Mammalian/mechanistic target of rapamycin (mTOR) complexes in neurodegeneration. https://t.co/fOO16gP9Or