Chapter title |
Competition for Iron Between Host and Pathogen: A Structural Case Study on Helicobacter pylori.
|
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Chapter number | 5 |
Book title |
Bacterial Pathogenesis
|
Published in |
Methods in molecular biology, January 2017
|
DOI | 10.1007/978-1-4939-6673-8_5 |
Pubmed ID | |
Book ISBNs |
978-1-4939-6671-4, 978-1-4939-6673-8
|
Authors |
Wei Xia |
Editors |
Pontus Nordenfelt, Mattias Collin |
Abstract |
Helicobacter pylori (H. pylori) is a highly successful bacterial pathogen, which colonizes the stomach of more than half of the world's population. To colonize and survive in such an acidic and inhospitable niche, H. pylori cells have evolved complex mechanisms to acquire nutrients from human hosts, including iron, an essential nutrient for both the pathogens and host cells. However, human cells also utilize diverse strategies in withholding of irons to prevent the bacterial outgrowth. The competition for iron is the central battlefield between pathogen and host. This mini-review summarizes the updated scenarios of the battle for iron between H. pylori and human host from a structural biology perspective. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 12 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 3 | 25% |
Student > Bachelor | 2 | 17% |
Lecturer | 1 | 8% |
Student > Doctoral Student | 1 | 8% |
Other | 1 | 8% |
Other | 4 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 5 | 42% |
Agricultural and Biological Sciences | 3 | 25% |
Immunology and Microbiology | 2 | 17% |
Chemical Engineering | 1 | 8% |
Medicine and Dentistry | 1 | 8% |
Other | 0 | 0% |