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Bacterial Pathogenesis

Overview of attention for book
Cover of 'Bacterial Pathogenesis'

Table of Contents

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    Book Overview
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    Chapter 1 Protein-Based Strategies to Identify and Isolate Bacterial Virulence Factors.
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    Chapter 2 Analysis of Bacterial Surface Interactions with Mass Spectrometry-Based Proteomics.
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    Chapter 3 Differential Radial Capillary Action of Ligand Assay (DRaCALA) for High-Throughput Detection of Protein-Metabolite Interactions in Bacteria.
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    Chapter 4 Identifying Bacterial Immune Evasion Proteins Using Phage Display.
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    Chapter 5 Competition for Iron Between Host and Pathogen: A Structural Case Study on Helicobacter pylori.
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    Chapter 6 Common Challenges in Studying the Structure and Function of Bacterial Proteins: Case Studies from Helicobacter pylori.
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    Chapter 7 Development of a Single Locus Sequence Typing (SLST) Scheme for Typing Bacterial Species Directly from Complex Communities.
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    Chapter 8 Reconstructing the Ancestral Relationships Between Bacterial Pathogen Genomes.
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    Chapter 9 Making Fluorescent Streptococci and Enterococci for Live Imaging.
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    Chapter 10 Computer Vision-Based Image Analysis of Bacteria.
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    Chapter 11 Assessing Vacuolar Escape of Listeria Monocytogenes.
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    Chapter 12 Immobilization Techniques of Bacteria for Live Super-resolution Imaging Using Structured Illumination Microscopy.
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    Chapter 13 Negative Staining and Transmission Electron Microscopy of Bacterial Surface Structures.
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    Chapter 14 Detection of Intracellular Proteins by High-Resolution Immunofluorescence Microscopy in Streptococcus pyogenes.
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    Chapter 15 Antibody Guided Molecular Imaging of Infective Endocarditis.
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    Chapter 16 The Zebrafish as a Model for Human Bacterial Infections.
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    Chapter 17 Determining Platelet Activation and Aggregation in Response to Bacteria.
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    Chapter 18 Killing Bacteria with Cytotoxic Effector Proteins of Human Killer Immune Cells: Granzymes, Granulysin, and Perforin.
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    Chapter 19 In Vitro and In Vivo Biofilm Formation by Pathogenic Streptococci.
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    Chapter 20 Murine Mycobacterium marinum Infection as a Model for Tuberculosis.
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    Chapter 21 Generating and Purifying Fab Fragments from Human and Mouse IgG Using the Bacterial Enzymes IdeS, SpeB and Kgp.
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    Chapter 22 Measuring Antibody Orientation at the Bacterial Surface.
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    Chapter 23 Toward Clinical use of the IgG Specific Enzymes IdeS and EndoS against Antibody-Mediated Diseases.
Attention for Chapter 16: The Zebrafish as a Model for Human Bacterial Infections.
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Chapter title
The Zebrafish as a Model for Human Bacterial Infections.
Chapter number 16
Book title
Bacterial Pathogenesis
Published in
Methods in molecular biology, January 2017
DOI 10.1007/978-1-4939-6673-8_16
Pubmed ID
Book ISBNs
978-1-4939-6671-4, 978-1-4939-6673-8
Authors

Melody N. Neely

Editors

Pontus Nordenfelt, Mattias Collin

Abstract

The development of the zebrafish (Danio rerio) infectious disease model has provided new insights and information into pathogenesis. Many of these new discoveries would not have been possible using a typical mammalian model. The advantages of using this model are many and in the last 15 years the model has been exploited for the analysis of many different pathogens. Here, we describe in detail how to perform a bacterial infection using either the adult zebrafish or zebrafish larvae using microinjection. Multiple methods of analysis are described that can be used to address specific questions pertaining to disease progression and the interactions with the immune system.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 4%
Unknown 23 96%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 4 17%
Student > Ph. D. Student 3 13%
Student > Master 3 13%
Lecturer 2 8%
Student > Bachelor 2 8%
Other 3 13%
Unknown 7 29%
Readers by discipline Count As %
Agricultural and Biological Sciences 4 17%
Biochemistry, Genetics and Molecular Biology 4 17%
Medicine and Dentistry 2 8%
Immunology and Microbiology 2 8%
Unspecified 1 4%
Other 2 8%
Unknown 9 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 January 2017.
All research outputs
#18,487,595
of 22,908,162 outputs
Outputs from Methods in molecular biology
#7,927
of 13,132 outputs
Outputs of similar age
#310,554
of 420,477 outputs
Outputs of similar age from Methods in molecular biology
#691
of 1,074 outputs
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So far Altmetric has tracked 13,132 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
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We're also able to compare this research output to 1,074 others from the same source and published within six weeks on either side of this one. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.