Title |
Discovering hidden relationships between renal diseases and regulated genes through 3D network visualizations
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Published in |
BMC Research Notes, November 2010
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DOI | 10.1186/1756-0500-3-296 |
Pubmed ID | |
Authors |
Suresh K Bhavnani, Arunkumaar Ganesan, Theodore Hall, Eric Maslowski, Felix Eichinger, Sebastian Martini, Paul Saxman, Gowtham Bellala, Matthias Kretzler |
Abstract |
In a recent study, two-dimensional (2D) network layouts were used to visualize and quantitatively analyze the relationship between chronic renal diseases and regulated genes. The results revealed complex relationships between disease type, gene specificity, and gene regulation type, which led to important insights about the underlying biological pathways. Here we describe an attempt to extend our understanding of these complex relationships by reanalyzing the data using three-dimensional (3D) network layouts, displayed through 2D and 3D viewing methods. |
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