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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Placental Hofbauer cells limit HIV-1 replication and potentially offset mother to child transmission (MTCT) by induction of immunoregulatory cytokines
|
|---|---|
| Published in |
Retrovirology, December 2012
|
| DOI | 10.1186/1742-4690-9-101 |
| Pubmed ID | |
| Authors |
Erica L Johnson, Rana Chakraborty |
| Abstract |
Despite readily detectable levels of the HIV-1 (co)-receptors CD4, CCR5 and DC-SIGN on placental macrophages (Hofbauer Cells [HCs]), the rate of HIV-1 infection in utero in the absence of interventions is only 7% of exposed infants. Here, we examine the replication kinetics of human HCs to the primary isolate HIV-1BaL. We also determined the infectivity of HIV-1-exposed HCs by co-culturing with isolated cord and peripheral blood mononuclear cells [CBMCs, PBMCs]. To understand the limiting nature of HCs to HIV-1 replication, we examined the effect of endogenously secreted cytokines on replication kinetics. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 92 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 1% |
| Puerto Rico | 1 | 1% |
| Brazil | 1 | 1% |
| Unknown | 89 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 18 | 20% |
| Researcher | 16 | 17% |
| Student > Doctoral Student | 12 | 13% |
| Student > Master | 9 | 10% |
| Student > Bachelor | 6 | 7% |
| Other | 13 | 14% |
| Unknown | 18 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 19 | 21% |
| Medicine and Dentistry | 16 | 17% |
| Immunology and Microbiology | 15 | 16% |
| Biochemistry, Genetics and Molecular Biology | 12 | 13% |
| Psychology | 5 | 5% |
| Other | 8 | 9% |
| Unknown | 17 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 May 2016.
All research outputs
#1,736,508
of 22,689,790 outputs
Outputs from Retrovirology
#74
of 1,103 outputs
Outputs of similar age
#16,746
of 277,751 outputs
Outputs of similar age from Retrovirology
#2
of 17 outputs
Altmetric has tracked 22,689,790 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,103 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 277,751 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.