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Mutation, Cancer, and Malformation
Overview of attention for book
Table of Contents
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Book Overview
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Chapter 1
Environmental Mutagenesis and Disease in Human Populations
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Chapter 2
Clinical Genetics of Human Cancer
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Chapter 3
Chromosome Abnormalities in Cancer Development
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Chapter 4
Mutations of Cellular Oncogenes as a Basis for Neoplastic Change
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Chapter 5
Human Gene Mapping in the Analysis of Oncogenes
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Chapter 6
Relationship between Mutagenesis and Carcinogenesis
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Chapter 7
Theoretical Basis of Mutagenesis
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Chapter 8
DNA Repair Processes
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Chapter 9
The Role of DNA Repair in Mutation Induction
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Chapter 10
Use of the Bacillus Subtilis Rec-Assay in Environmental Mutagen Studies
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Chapter 11
Mutagenesis in Yeasts
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Chapter 12
A Comparison of Genotoxic Activity in Somatic Tissue and in Germ Cells of Drosophila Melanogaster
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Chapter 13
The P-Factor: A Transposable Element in Drosophila
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Chapter 14
Silkworm Genetics and Chemical Mutagenesis
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Chapter 15
Mutation Induction and Detection in Arabidopsis
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Chapter 16
Mutagenesis Studies with Cultured Mammalian Cells: Problems and Prospects
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Chapter 17
The Control of Cell Transformation, Mutagenesis, and Differentiation by Chemicals that Initiate or Promote Tumor Formation
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Chapter 18
Dominant-Lethal Mutations and Heritable Translocations in Mice
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Chapter 19
Recessive and Dominant Mutations in Mice
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Chapter 20
Benzo (a) Pyrene and 6-Nitrobenzo (a) Pyrene Metabolism in Human and Rodent Microsomes and Tissue Culture
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Chapter 21
Nitrosamine Metabolism and Carcinogenesis
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Chapter 22
Modification of Carcinogenesis by Dietary and Nutritional Factors
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Chapter 23
Naturally Occurring Mutagens
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Chapter 24
Teratogenesis
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Chapter 25
A Possible Mechanistic Link between Teratogenesis and Carcinogenesis: Inhibited Intercellular Communication
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Chapter 26
Germ Cell Toxicity: Significance in Genetic and Fertility Effects of Radiation and Chemicals
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Chapter 27
The Science of Toxicology-Scope, Goals and Four Case Studies
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Chapter 28
Mutagenicity of Pesticides
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Chapter 29
Genetic Toxicology of 14 Agents Causally Associated with Cancer in Humans
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Chapter 30
Sensitivity, Specificity and Accuracy of the Arabidopsis Assay in the Identification of Carcinogens
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Chapter 31
Environmental Studies in Sweden
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Chapter 32
Research Progress on Environmental Mutagenesis, Carcinogenesis and Teratogenesis in China
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Chapter 33
A Strategy of Approach to Cancer Control in China
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Chapter 34
Toxicological Research in Public Health: The Chinese Experience
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Chapter 35
Environmental Mutagenesis Research at Fudan University
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Chapter 36
The Role of Risk Assessment in Regulatory Decisions in the United States
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Chapter 37
Alternate Methods for Integrated Evaluation of Toxicity and Risk Assessment
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Chapter 38
Lymphocyte Chromosome Aberrations in Persons Exposed to Low Levels of Radiation
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Chapter 39
Cytogenetic Follow-Up Studies in Persons Accidentally Exposed to 60 Co γ-Rays, 10 Years After Exposure
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Chapter 40
Studies on Micronucleus Test by Human Skin Puncture
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Chapter 41
Comparison of the Responses of the Micronucleus Test in Different Strains of Mice
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Chapter 42
Study on the Micronucleus in Nucleated Erythrocytes in Vertebrates and its Application to Monitoring Environmental Pollution
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Chapter 43
Chromosome Aberrations in Human Lymphocytes Induced by Tritium
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Chapter 44
The Effect of Gossypol on Human Lymphocytes In Vitro : Cell Kinetics, Traditional Chromosome Breakage, Micronuclei, and Sister Chromatid Exchange
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Chapter 45
Induction of Sister Chromatid Exchanges with “Compound Presciption Progestogen No. 1” in the Maternal and Embryonic Tissues of Mice
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Chapter 46
Induction of Sister Chromatid Exchanges with Gossypol Acetate in Mouse Spermatogonial Cells In Vivo
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Chapter 47
The Influence of Oral Contraceptive on Silver-Stained Acrocentric Association
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Chapter 48
Cytotoxicity and Induction of Sister Chromatid Exchanges (SCE) In Vitro by Several Antitumor Drugs
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Chapter 49
The Induction of Sister Chromatid Exchanges in Human Gastric Carcinoma Cells and Lymphocytes Exposed to Anti-Tumor Drugs
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Chapter 50
Influence of 2450 MHz Microwave Radiation on Sister Chromatid Exchange (SCE) of Human Lymphocytes in Short Term Culture
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Chapter 51
Sister Chromatid Exchanges in Lymphocytes of Bufo Bufo Gargarizans as an Environmental Mutagenecity Assay
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Chapter 52
A Modified Method of UDS Estimation In Vitro Suitable for Screening the DNA-Damaging Effects of Chemicals
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Chapter 53
Effects of Several Kinds of Radiosensitizers on γ-Ray-Induced DNA Single Strand Breaks and their Rejoining in Mammalian Cells
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Chapter 54
Effects of Interferon on Mitomycin-Induced Sister Chromatid Exchanges and on Ultraviolet-Light-Induced Unscheduled DNA Synthesis
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Chapter 55
Isolation and Identification of Direct-Acting Mutagens in Diesel Exhaust
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Chapter 56
Aphidicolin Induces Endoreduplication in Chinese Hamster Cells
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Chapter 57
Search for Carcinogenic Agents in the Shanghai Rubber Industry
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Chapter 58
Induction of Lung Cancer in Wistar Rats by Tin Ore Dust Containing Arsenicals
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Chapter 59
Carcinogenicity of Extract of Soot from Xuan Wei County after Administering Subcutaneously to Mice
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Chapter 60
Study on the Carcinogenicity of Chlordimeform III. Long-Term Feeding Assay in Mice
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Chapter 61
Induction of Tumor in the Progeny of Dinitrosopiperazine-Treated Pregnant Rats
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Chapter 62
Promoting Effect and Related Actions of TPA on C3H/10T1/2 Cells
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Chapter 63
Malignant Transformation of Mouse Bone Marrow Cells In Vitro Induced by 60 Co γ-Ray Irradiation
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Chapter 64
Some Biological Characteristics of MNNG-Transformed Cells In Vitro
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Chapter 65
Study of Carcinogenic Mechanism for Polycyclic Aromatic Hydrocarbons: Extended Bay Region Theory and Its Quantitative Model
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Chapter 66
The Combined Action of Polycyclic Aromatic Hydrocarbons (PAH) on the Activity of Aryl Hydrocarbon Hydroxylase (AHH): In Vitro Assay
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Chapter 67
Epidemiological Survey on the Teratogenic Effect of MATDA [Methylene-Bis-(2-Amino-1,3,4-Thiadiazole)]
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Chapter 68
Mutagenecity Study of V 2 O 5
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Chapter 69
Mutagenicity and Teratogenicity of the Fungicide Ethyl Disulfide
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Chapter 70
The Frequency of Sister Chromatid Exchange in Peripheral Lymphocytes of Workers Exposed to TNT
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Chapter 71
Studies on the Malignant Transformation of Mouse Bone Marrow Cells In Vitro Induced by 60 Co γ-Ray Irradiation
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Chapter 72
Dominant Lethal Mutations Induced by Tritiated Water and 60 Co Gamma Rays in Female Mice
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Chapter 73
Inhibitory Effects of Phenolic or Hydroxy Compounds on the Metabolism of Benzo(a)Pyrene
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Chapter 74
A Preliminary Observation on the Mutagenic Effect of Dibromochloropropane (DBCP) in Drosophila Melanogaster Sex-Linked Recessive Lethal Test
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Chapter 75
Regression Analysis of 60 CO Irradiation and Pinyangmycin Induced Micronuclei and Chromosomal Aberrations in the Root Tip Cells of Vicia Faba
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Chapter 76
Lung Cancer and Exposure to Chloro-Methyl-Ethers —An Occupational Epidemiological Survey
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Chapter 77
Studies on the Mutagenicity and Teratogenicity of Methyl-Parathion
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Chapter 78
Study on the Carcinogenecity of γ-Benzene-Hexachloride in Rats
Overall attention for this book and its chapters
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Book overview
1. Environmental Mutagenesis and Disease in Human Populations
2. Clinical Genetics of Human Cancer
3. Chromosome Abnormalities in Cancer Development
4. Mutations of Cellular Oncogenes as a Basis for Neoplastic Change
5. Human Gene Mapping in the Analysis of Oncogenes
6. Relationship between Mutagenesis and Carcinogenesis
7. Theoretical Basis of Mutagenesis
8. DNA Repair Processes
9. The Role of DNA Repair in Mutation Induction
10. Use of the Bacillus Subtilis Rec-Assay in Environmental Mutagen Studies
11. Mutagenesis in Yeasts
12. A Comparison of Genotoxic Activity in Somatic Tissue and in Germ Cells of Drosophila Melanogaster
13. The P-Factor: A Transposable Element in Drosophila
14. Silkworm Genetics and Chemical Mutagenesis
15. Mutation Induction and Detection in Arabidopsis
16. Mutagenesis Studies with Cultured Mammalian Cells: Problems and Prospects
17. The Control of Cell Transformation, Mutagenesis, and Differentiation by Chemicals that Initiate or Promote Tumor Formation
18. Dominant-Lethal Mutations and Heritable Translocations in Mice
19. Recessive and Dominant Mutations in Mice
20. Benzo (a) Pyrene and 6-Nitrobenzo (a) Pyrene Metabolism in Human and Rodent Microsomes and Tissue Culture
21. Nitrosamine Metabolism and Carcinogenesis
22. Modification of Carcinogenesis by Dietary and Nutritional Factors
23. Naturally Occurring Mutagens
24. Teratogenesis
25. A Possible Mechanistic Link between Teratogenesis and Carcinogenesis: Inhibited Intercellular Communication
26. Germ Cell Toxicity: Significance in Genetic and Fertility Effects of Radiation and Chemicals
27. The Science of Toxicology-Scope, Goals and Four Case Studies
28. Mutagenicity of Pesticides
29. Genetic Toxicology of 14 Agents Causally Associated with Cancer in Humans
30. Sensitivity, Specificity and Accuracy of the Arabidopsis Assay in the Identification of Carcinogens
31. Environmental Studies in Sweden
32. Research Progress on Environmental Mutagenesis, Carcinogenesis and Teratogenesis in China
33. A Strategy of Approach to Cancer Control in China
34. Toxicological Research in Public Health: The Chinese Experience
35. Environmental Mutagenesis Research at Fudan University
36. The Role of Risk Assessment in Regulatory Decisions in the United States
37. Alternate Methods for Integrated Evaluation of Toxicity and Risk Assessment
38. Lymphocyte Chromosome Aberrations in Persons Exposed to Low Levels of Radiation
39. Cytogenetic Follow-Up Studies in Persons Accidentally Exposed to 60 Co γ-Rays, 10 Years After Exposure
40. Studies on Micronucleus Test by Human Skin Puncture
41. Comparison of the Responses of the Micronucleus Test in Different Strains of Mice
42. Study on the Micronucleus in Nucleated Erythrocytes in Vertebrates and its Application to Monitoring Environmental Pollution
43. Chromosome Aberrations in Human Lymphocytes Induced by Tritium
44. The Effect of Gossypol on Human Lymphocytes In Vitro : Cell Kinetics, Traditional Chromosome Breakage, Micronuclei, and Sister Chromatid Exchange
45. Induction of Sister Chromatid Exchanges with “Compound Presciption Progestogen No. 1” in the Maternal and Embryonic Tissues of Mice
46. Induction of Sister Chromatid Exchanges with Gossypol Acetate in Mouse Spermatogonial Cells In Vivo
47. The Influence of Oral Contraceptive on Silver-Stained Acrocentric Association
48. Cytotoxicity and Induction of Sister Chromatid Exchanges (SCE) In Vitro by Several Antitumor Drugs
49. The Induction of Sister Chromatid Exchanges in Human Gastric Carcinoma Cells and Lymphocytes Exposed to Anti-Tumor Drugs
50. Influence of 2450 MHz Microwave Radiation on Sister Chromatid Exchange (SCE) of Human Lymphocytes in Short Term Culture
51. Sister Chromatid Exchanges in Lymphocytes of Bufo Bufo Gargarizans as an Environmental Mutagenecity Assay
52. A Modified Method of UDS Estimation In Vitro Suitable for Screening the DNA-Damaging Effects of Chemicals
53. Effects of Several Kinds of Radiosensitizers on γ-Ray-Induced DNA Single Strand Breaks and their Rejoining in Mammalian Cells
54. Effects of Interferon on Mitomycin-Induced Sister Chromatid Exchanges and on Ultraviolet-Light-Induced Unscheduled DNA Synthesis
55. Isolation and Identification of Direct-Acting Mutagens in Diesel Exhaust
56. Aphidicolin Induces Endoreduplication in Chinese Hamster Cells
57. Search for Carcinogenic Agents in the Shanghai Rubber Industry
58. Induction of Lung Cancer in Wistar Rats by Tin Ore Dust Containing Arsenicals
59. Carcinogenicity of Extract of Soot from Xuan Wei County after Administering Subcutaneously to Mice
60. Study on the Carcinogenicity of Chlordimeform III. Long-Term Feeding Assay in Mice
61. Induction of Tumor in the Progeny of Dinitrosopiperazine-Treated Pregnant Rats
62. Promoting Effect and Related Actions of TPA on C3H/10T1/2 Cells
63. Malignant Transformation of Mouse Bone Marrow Cells In Vitro Induced by 60 Co γ-Ray Irradiation
64. Some Biological Characteristics of MNNG-Transformed Cells In Vitro
65. Study of Carcinogenic Mechanism for Polycyclic Aromatic Hydrocarbons: Extended Bay Region Theory and Its Quantitative Model
66. The Combined Action of Polycyclic Aromatic Hydrocarbons (PAH) on the Activity of Aryl Hydrocarbon Hydroxylase (AHH): In Vitro Assay
67. Epidemiological Survey on the Teratogenic Effect of MATDA [Methylene-Bis-(2-Amino-1,3,4-Thiadiazole)]
68. Mutagenecity Study of V 2 O 5
69. Mutagenicity and Teratogenicity of the Fungicide Ethyl Disulfide
70. The Frequency of Sister Chromatid Exchange in Peripheral Lymphocytes of Workers Exposed to TNT
71. Studies on the Malignant Transformation of Mouse Bone Marrow Cells In Vitro Induced by 60 Co γ-Ray Irradiation
72. Dominant Lethal Mutations Induced by Tritiated Water and 60 Co Gamma Rays in Female Mice
73. Inhibitory Effects of Phenolic or Hydroxy Compounds on the Metabolism of Benzo(a)Pyrene
74. A Preliminary Observation on the Mutagenic Effect of Dibromochloropropane (DBCP) in Drosophila Melanogaster Sex-Linked Recessive Lethal Test
75. Regression Analysis of 60 CO Irradiation and Pinyangmycin Induced Micronuclei and Chromosomal Aberrations in the Root Tip Cells of Vicia Faba
76. Lung Cancer and Exposure to Chloro-Methyl-Ethers —An Occupational Epidemiological Survey
77. Studies on the Mutagenicity and Teratogenicity of Methyl-Parathion
78. Study on the Carcinogenecity of γ-Benzene-Hexachloride in Rats
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