RT @christophestove: Interesting read! 👉 2 common occurring variants of CB2R (Q63R & L133I) 👉 binding profile of these mutant receptors to…
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Interesting read! 👉 2 common occurring variants of CB2R (Q63R & L133I) 👉 binding profile of these mutant receptors to G proteins & β-arr2: ✴ similar ability to ⬇ cAMP signaling ✴ Q63R mutant had ⬆, whereas the L133I mutant had ⬇ β-arr2 binding. 👇 h
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Biased Coupling to beta-Arrestin of Two Common Variants of the CB(2) Cannabinoid Receptor https://t.co/HKLy53htPF #GPCR #signaling #pharmacology
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RT @FrontEndocrinol: New Research: Biased Coupling to β-Arrestin of Two Common Variants of the CB2 Cannabinoid Receptor: β-arrestins are pa…