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Biologic activity of the novel small molecule STAT3 inhibitor LLL12 against canine osteosarcoma cell lines

Overview of attention for article published in BMC Veterinary Research, December 2012
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (73rd percentile)
  • High Attention Score compared to outputs of the same age and source (85th percentile)

Mentioned by

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6 X users
facebook
1 Facebook page
googleplus
1 Google+ user

Citations

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23 Dimensions

Readers on

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46 Mendeley
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Title
Biologic activity of the novel small molecule STAT3 inhibitor LLL12 against canine osteosarcoma cell lines
Published in
BMC Veterinary Research, December 2012
DOI 10.1186/1746-6148-8-244
Pubmed ID
Authors

Jason I Couto, Misty D Bear, Jiayuh Lin, Michael Pennel, Samuel K Kulp, William C Kisseberth, Cheryl A London

Abstract

STAT3 [1] has been shown to be dysregulated in nearly every major cancer, including osteosarcoma (OS). Constitutive activation of STAT3, via aberrant phosphorylation, leads to proliferation, cell survival and resistance to apoptosis. The present study sought to characterize the biologic activity of a novel allosteric STAT3 inhibitor, LLL12, in canine OS cell lines.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 45 98%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 10 22%
Other 9 20%
Researcher 5 11%
Student > Ph. D. Student 4 9%
Student > Master 4 9%
Other 10 22%
Unknown 4 9%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 15 33%
Medicine and Dentistry 15 33%
Agricultural and Biological Sciences 7 15%
Chemistry 2 4%
Immunology and Microbiology 1 2%
Other 1 2%
Unknown 5 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 December 2012.
All research outputs
#6,757,142
of 22,689,790 outputs
Outputs from BMC Veterinary Research
#501
of 3,034 outputs
Outputs of similar age
#67,819
of 261,293 outputs
Outputs of similar age from BMC Veterinary Research
#13
of 88 outputs
Altmetric has tracked 22,689,790 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 3,034 research outputs from this source. They receive a mean Attention Score of 3.8. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 261,293 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 88 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.