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Expression of epithelial to mesenchymal transition-related markers in lymph node metastases as a surrogate for primary tumor metastatic potential in breast cancer

Overview of attention for article published in Journal of Translational Medicine, November 2012
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Title
Expression of epithelial to mesenchymal transition-related markers in lymph node metastases as a surrogate for primary tumor metastatic potential in breast cancer
Published in
Journal of Translational Medicine, November 2012
DOI 10.1186/1479-5876-10-226
Pubmed ID
Authors

Aleksandra Markiewicz, Tomasz Ahrends, Marzena Wełnicka-Jaśkiewicz, Barbara Seroczyńska, Jarosław Skokowski, Janusz Jaśkiewicz, Jolanta Szade, Wojciech Biernat, Anna J Żaczek

Abstract

Breast cancers are phenotypically and genotypically heterogeneous tumors containing multiple cancer cell populations with various metastatic potential. Aggressive tumor cell subpopulations might more easily be captured in lymph nodes metastases (LNM) than in primary tumors (PT). We evaluated mRNA and protein levels of master EMT regulators: TWIST1, SNAIL and SLUG, protein levels of EMT-related markers: E-cadherin, vimentin, and expression of classical breast cancer receptors: HER2, ER and PgR in PT and corresponding LNM. The results were correlated with clinicopathological data and patients outcomes.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 5%
Brazil 2 5%
Serbia 1 2%
Unknown 37 88%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 19%
Student > Doctoral Student 6 14%
Student > Master 6 14%
Student > Bachelor 5 12%
Other 5 12%
Other 5 12%
Unknown 7 17%
Readers by discipline Count As %
Medicine and Dentistry 15 36%
Agricultural and Biological Sciences 13 31%
Biochemistry, Genetics and Molecular Biology 2 5%
Chemical Engineering 1 2%
Immunology and Microbiology 1 2%
Other 1 2%
Unknown 9 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 December 2012.
All research outputs
#18,325,190
of 22,691,736 outputs
Outputs from Journal of Translational Medicine
#2,936
of 3,965 outputs
Outputs of similar age
#214,202
of 276,044 outputs
Outputs of similar age from Journal of Translational Medicine
#60
of 91 outputs
Altmetric has tracked 22,691,736 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,965 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one is in the 16th percentile – i.e., 16% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 276,044 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 91 others from the same source and published within six weeks on either side of this one. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.