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Alphaherpesvirinae and Gammaherpesvirinae glycoprotein L and CMV UL130 originate from chemokines

Overview of attention for article published in Virology Journal, January 2013
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (56th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (51st percentile)

Mentioned by

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3 tweeters

Citations

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78 Dimensions

Readers on

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12 Mendeley
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Title
Alphaherpesvirinae and Gammaherpesvirinae glycoprotein L and CMV UL130 originate from chemokines
Published in
Virology Journal, January 2013
DOI 10.1186/1743-422x-10-1
Pubmed ID
Authors

Maja Malkowska, Katarzyna Kokoszynska, Magdalena Dymecka, Leszek Rychlewski, Lucjan S Wyrwicz

Abstract

Herpesviridae is a large family of DNA viruses divided into three subfamilies: Alpha-, Beta- and Gammaherpesvirinae. The process of herpesvirus transmission is mediated by a range of proteins, one of which is glycoprotein L (gL). Based on our analysis of the solved structures of HSV2 and EBV gH/gL complexes, we propose that Alphaherpesvirinae and Gammaherpesvirinae glycoprotein L and Betaherpesvirinae UL130 originate from chemokines. Herpes simplex virus type 2 gL and human cytomegalovirus homolog (UL130) adopt a novel C chemokine-like fold, while Epstein-Barr virus gL mimics a CC chemokine structure. Hence, it is possible that gL interface with specific chemokine receptors during the transmission of Herpesviridae. We conclude that the further understanding of the function of viral chemokine-like proteins in Herpesviridae infection may lead to development of novel prophylactic and therapeutic treatment.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 8%
Sudan 1 8%
Unknown 10 83%

Demographic breakdown

Readers by professional status Count As %
Student > Master 3 25%
Student > Bachelor 3 25%
Student > Doctoral Student 2 17%
Researcher 2 17%
Professor > Associate Professor 1 8%
Other 1 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 58%
Biochemistry, Genetics and Molecular Biology 3 25%
Pharmacology, Toxicology and Pharmaceutical Science 1 8%
Veterinary Science and Veterinary Medicine 1 8%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 January 2013.
All research outputs
#1,990,109
of 4,507,211 outputs
Outputs from Virology Journal
#569
of 1,270 outputs
Outputs of similar age
#115,555
of 283,433 outputs
Outputs of similar age from Virology Journal
#40
of 91 outputs
Altmetric has tracked 4,507,211 research outputs across all sources so far. This one has received more attention than most of these and is in the 53rd percentile.
So far Altmetric has tracked 1,270 research outputs from this source. They receive a mean Attention Score of 3.1. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 283,433 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.
We're also able to compare this research output to 91 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.