Title |
Degenerative suspensory ligament desmitis as a systemic disorder characterized by proteoglycan accumulation
|
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Published in |
BMC Veterinary Research, April 2006
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DOI | 10.1186/1746-6148-2-12 |
Pubmed ID | |
Authors |
Jaroslava Halper, Byoungjae Kim, Ahrar Khan, Jung Hae Yoon, PO Eric Mueller |
Abstract |
Degenerative suspensory ligament desmitis (DSLD) is a debilitating disorder thought to be limited to suspensory ligaments of Peruvian Pasos, Peruvian Paso crosses, Arabians, American Saddlebreds, American Quarter Horses, Thoroughbreds, and some European breeds. It frequently leads to persistent, incurable lameness and need to euthanize affected horses. The pathogenesis remains unclear, though the disease appears to run in families. Treatment and prevention are empirical and supportive, and not effective in halting the progression of the disease. Presently, the presumptive diagnosis of DSLD is obtained from patient signalment and history, clinical examination, and ultrasonographic examination of clinically affected horses, and is confirmed at post mortem examination. Presently, there are no reliable methods of diagnosing DSLD in asymptomatic horses. The goal of this study was to characterize and define the disorder in terms of tissue involvement at the macroscopic and microscopic levels. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
South Africa | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 1% |
United States | 1 | 1% |
Unknown | 87 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 17 | 19% |
Student > Master | 13 | 15% |
Other | 9 | 10% |
Student > Doctoral Student | 6 | 7% |
Researcher | 6 | 7% |
Other | 20 | 22% |
Unknown | 18 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Veterinary Science and Veterinary Medicine | 28 | 31% |
Medicine and Dentistry | 18 | 20% |
Agricultural and Biological Sciences | 12 | 13% |
Biochemistry, Genetics and Molecular Biology | 4 | 4% |
Nursing and Health Professions | 2 | 2% |
Other | 6 | 7% |
Unknown | 19 | 21% |