Report for: The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells

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Title	The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells
Published in	Nature Neuroscience, October 2021
DOI	10.1038/s41593-021-00926-1
Pubmed ID	34675436
Authors	Jan Wenzel, Josephine Lampe, Helge Müller-Fielitz, Raphael Schuster, Marietta Zille, Kristin Müller, Markus Krohn, Jakob Körbelin, Linlin Zhang, Ümit Özorhan, Vanessa Neve, Julian U. G. Wagner, Denisa Bojkova, Mariana Shumliakivska, Yun Jiang, Anke Fähnrich, Fabian Ott, Valentin Sencio, Cyril Robil, Susanne Pfefferle, Florent Sauve, Caio Fernando Ferreira Coêlho, Jonas Franz, Frauke Spiecker, Beate Lembrich, Sonja Binder, Nina Feller, Peter König, Hauke Busch, Ludovic Collin, Roberto Villaseñor, Olaf Jöhren, Hermann C. Altmeppen, Manolis Pasparakis, Stefanie Dimmeler, Jindrich Cinatl, Klaus Püschel, Matija Zelic, Dimitry Ofengeim, Christine Stadelmann, François Trottein, Ruben Nogueiras, Rolf Hilgenfeld, Markus Glatzel, Vincent Prevot, Markus Schwaninger

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Twitter Demographics

The data shown below were collected from the profiles of 6,641 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Geographical breakdown

Country	Count	As %
United States	809	12%
Germany	379	6%
United Kingdom	329	5%
Canada	314	5%
Australia	130	2%
Italy	127	2%
France	121	2%
Japan	101	2%
Spain	77	1%
Other	743	11%
Unknown	3511	53%

Demographic breakdown

Type	Count	As %
Members of the public	5756	87%
Scientists	483	7%
Practitioners (doctors, other healthcare professionals)	284	4%
Science communicators (journalists, bloggers, editors)	109	2%
Unknown	9	<1%

Mendeley readers

The data shown below were compiled from readership statistics for 177 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country	Count	As %
Unknown	177	100%

Demographic breakdown

Readers by professional status	Count	As %
Researcher	35	20%
Student > Ph. D. Student	16	9%
Student > Master	16	9%
Other	13	7%
Student > Bachelor	11	6%
Other	33	19%
Unknown	53	30%

Readers by discipline	Count	As %
Biochemistry, Genetics and Molecular Biology	29	16%
Neuroscience	19	11%
Medicine and Dentistry	18	10%
Agricultural and Biological Sciences	10	6%
Immunology and Microbiology	7	4%
Other	34	19%
Unknown	60	34%

Attention Score in Context

This research output has an Altmetric Attention Score of 4097. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 May 2023.

All research outputs

#1,093

of 23,866,543 outputs

Outputs from Nature Neuroscience

of 5,356 outputs

Outputs of similar age

#75

of 442,095 outputs

Outputs of similar age from Nature Neuroscience

of 57 outputs

Altmetric has tracked 23,866,543 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.

So far Altmetric has tracked 5,356 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 55.4. This one has done particularly well, scoring higher than 99% of its peers.

Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 442,095 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.

We're also able to compare this research output to 57 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.

The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells

About this Attention Score

Mentioned by

Citations

Readers on

Twitter Demographics

Geographical breakdown

Demographic breakdown

Mendeley readers

Geographical breakdown

Demographic breakdown

Attention Score in Context