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The impact of voluntary exercise on relative telomere length in a rat model of developmental stress

Overview of attention for article published in BMC Research Notes, December 2012
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Title
The impact of voluntary exercise on relative telomere length in a rat model of developmental stress
Published in
BMC Research Notes, December 2012
DOI 10.1186/1756-0500-5-697
Pubmed ID
Authors

Martmari Botha, Laurian Grace, Kishor Bugarith, Vivienne A Russell, Martin Kidd, Soraya Seedat, Sian MJ Hemmings

Abstract

Exposure to early adverse events can result in the development of later psychopathology, and is often associated with cognitive impairment. This may be due to accelerated cell aging, which can be catalogued by attritioned telomeres. Exercise enhances neurogenesis and has been proposed to buffer the effect of psychological stress on telomere length. This study aimed to investigate the impact of early developmental stress and voluntary exercise on telomere length in the ventral hippocampus (VH) and prefrontal cortex (PFC) of the rat. Forty-five male Sprague-Dawley rats were categorised into four groups: maternally separated runners (MSR), maternally separated non-runners (MSnR), non-maternally separated runners (nMSR) and non-maternally separated non-runners (nMSnR). Behavioural analyses were conducted to assess anxiety-like behaviour and memory performance in the rats, after which relative telomere length was measured using qPCR.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 90 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 2%
United States 2 2%
Brazil 1 1%
Unknown 85 94%

Demographic breakdown

Readers by professional status Count As %
Student > Master 16 18%
Student > Ph. D. Student 16 18%
Researcher 15 17%
Student > Doctoral Student 11 12%
Student > Bachelor 8 9%
Other 12 13%
Unknown 12 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 20 22%
Medicine and Dentistry 15 17%
Neuroscience 12 13%
Psychology 10 11%
Biochemistry, Genetics and Molecular Biology 6 7%
Other 11 12%
Unknown 16 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 January 2013.
All research outputs
#18,325,190
of 22,691,736 outputs
Outputs from BMC Research Notes
#3,009
of 4,255 outputs
Outputs of similar age
#217,907
of 280,466 outputs
Outputs of similar age from BMC Research Notes
#32
of 54 outputs
Altmetric has tracked 22,691,736 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,255 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one is in the 16th percentile – i.e., 16% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,466 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 54 others from the same source and published within six weeks on either side of this one. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.